CRHR2

Gene Name		corticotropin releasing hormone receptor 2
Image
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Hormone Activity Protein Binding Corticotrophin-releasing Factor Receptor Activity
	Biological Process	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Angiogenesis Positive Regulation Of CAMP-mediated Signaling Negative Regulation Of CAMP-mediated Signaling Cellular Response To Corticotropin-releasing Hormone Stimulus
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: APP CRH UCN UCN2 UCN3
Entrez ID		1395
HPRD ID		03614
Ensembl ID
Uniprot IDs		B2R967 B3SXS6 B3SXT0 Q13324
PDB IDs		3N93 3N95 3N96
Enriched GO Terms of Interacting Partners?		Response To Immobilization Stress Response To Glucocorticoid Response To Corticosteroid Regulation Of Hormone Secretion Positive Regulation Of Corticotropin Secretion Negative Regulation Of Luteinizing Hormone Secretion Negative Regulation Of Hormone Secretion Regulation Of Corticotropin Secretion Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Associative Learning Feeding Behavior Positive Regulation Of Behavioral Fear Response Negative Regulation Of Gonadotropin Secretion Response To Steroid Hormone Positive Regulation Of Hormone Secretion Digestion Learning Regulation Of Secretion Positive Regulation Of Calcium Ion Import Negative Regulation Of Secretion By Cell Negative Regulation Of Secretion Regulation Of Peptide Hormone Secretion Response To Lipid Regulation Of Calcium Ion Import Response To Organic Cyclic Compound Response To Hormone Learning Or Memory Regulation Of Cellular Localization Cognition Response To Corticosterone Response To Abiotic Stimulus Positive Regulation Of Secretion Response To Mineralocorticoid Response To Pain Regulation Of Signaling Negative Regulation Of Blood Pressure Negative Regulation Of Transport Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Response To Nutrient Levels Positive Regulation Of CAMP Biosynthetic Process Single-organism Behavior Response To Stress Response To Extracellular Stimulus Positive Regulation Of Insulin Secretion Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Ion Transmembrane Transport Positive Regulation Of Cyclic Nucleotide Metabolic Process
Tagcloud ?		amygdala cns corticosterone corticotropin crf2 disparity drinking f2 gs inbred inp ip lowered maps minute nonpreferring np polymorphism preference preferring qtl releasing restraint screen trait ucns untranslated urocortins