VPS37A

Description		VPS37A subunit of ESCRT-I
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GO Annotations	Cellular Component	ESCRT I Complex Nucleus Nucleoplasm Endosome Centrosome Cytosol Endosome Membrane Membrane Late Endosome Membrane
	Molecular Function	Protein Binding
	Biological Process	Protein Targeting To Membrane Protein Targeting To Vacuole Protein Transport Macroautophagy Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Fission
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Schizophrenia ( 28991256) Tonometry ( 17903302)
Interacting Genes		9 interacting genes: APP HGS KDM1A TRIM42 TRIM55 TRIM63 TSG101 UBC VPS28
Entrez ID		137492
HPRD ID		13410
Ensembl ID		ENSG00000155975
Uniprot IDs		Q8NEZ2
PDB IDs		8E22
Enriched GO Terms of Interacting Partners?		Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Ubiquitin-dependent Endocytosis Multivesicular Body Organization Multivesicular Body Assembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Fission Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Protein Metabolic Process Endosome Organization Protein Localization To Vacuole ESCRT I Complex Early Endosome Ubiquitin Binding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Viral Budding Via Host ESCRT Complex Positive Regulation Of Endocytosis Macroautophagy Viral Budding Vacuolar Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Neuron Maturation Regulation Of Vesicle-mediated Transport Regulation Of Phosphorus Metabolic Process Early Endosome Membrane Protein Ubiquitination Regulation Of Protein Modification Process Positive Regulation Of Protein Transport Macromolecule Metabolic Process Endosomal Transport Protein Modification By Small Protein Conjugation Regulation Of Glycolytic Process Endosome Membrane Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Establishment Of Protein Localization Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Endosome Amylin Binding Regulation Of Protein Metabolic Process Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Endocytosis Vesicle Organization Autophagy
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