VPS37A

Gene Name		vacuolar protein sorting 37 homolog A (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	ESCRT I Complex Nucleoplasm Cytoplasm Centrosome Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function
	Biological Process	Protein Transport Viral Process Endosomal Transport Viral Life Cycle Virion Assembly Viral Protein Processing Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Intracellular Transport Of Virus
Pathways		Assembly Of The HIV Virion Synthesis And Processing Of GAG, GAGPOL Polyproteins HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Membrane binding and targetting of GAG proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS		Tonometry ( 17903302)
Protein-protein Interactions		6 interactors: APP HGS KDM1A TRIM42 TSG101 VPS28
Entrez ID		137492
HPRD ID		13410
Ensembl ID		ENSG00000155975
Uniprot IDs		Q8NEZ2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Viral Protein Processing Endosomal Transport Protein Targeting To Vacuole Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Intracellular Transport Of Virus Positive Regulation Of Exocytosis Intracellular Transport Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vacuolar Transport Regulation Of ERBB Signaling Pathway Regulation Of Primitive Erythrocyte Differentiation Establishment Of Localization In Cell Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Protein Binding Negative Regulation Of Cellular Protein Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of Exocytosis Membrane Organization Negative Regulation Of Protein Metabolic Process Cellular Localization Collateral Sprouting In Absence Of Injury Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Life Cycle Collateral Sprouting Axon Midline Choice Point Recognition Protein Processing Regulation Of Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Extracellular Vesicular Exosome Assembly Endosome Transport Via Multivesicular Body Sorting Pathway Axon Choice Point Recognition Late Endosome To Vacuole Transport Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Viral Budding Positive Regulation Of Secretion Neuron Remodeling Protein Transport Gene Expression Positive Regulation Of Megakaryocyte Differentiation Establishment Of Protein Localization To Organelle Establishment Of Protein Localization Regulation Of Cell Proliferation Regulation Of Vesicle-mediated Transport
Tagcloud ?		acidic alpha2 alpha2beta1 biogenesis bodies clustering dil downregulation echovirus endosomal endosomes enveloped escrts ev1 integrin internalization internalized lbpa live lysosomal lysosomes multivesicular mvbs picornavirus separate tsg101 vesicles vps24 vps4