HUS1B

Description		HUS1 checkpoint clamp component B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Checkpoint Clamp Complex Site Of Double-strand Break
	Molecular Function
	Biological Process	DNA Damage Checkpoint Signaling Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Nucleotide-excision Repair Mitotic Intra-S DNA Damage Checkpoint Signaling Mitotic DNA Replication Checkpoint Signaling Meiotic DNA Integrity Checkpoint Signaling
Pathways
Drugs
Diseases
GWAS		Aging ( 22773346) Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: HUS1 RAD1 RAD9A RAD9B
Entrez ID		135458
HPRD ID		13722
Ensembl ID		ENSG00000188996
Uniprot IDs		Q8NHY5
PDB IDs
Enriched GO Terms of Interacting Partners?		Checkpoint Clamp Complex Cellular Response To Ionizing Radiation DNA Damage Checkpoint Signaling Mitotic Intra-S DNA Damage Checkpoint Signaling DNA Replication Checkpoint Signaling Response To Ionizing Radiation Signal Transduction In Response To DNA Damage Cellular Response To Radiation Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Mitotic DNA Damage Checkpoint Signaling Mitotic DNA Integrity Checkpoint Signaling Response To Radiation Regulation Of Cell Cycle Phase Transition Double-stranded DNA 3'-5' DNA Exonuclease Activity DNA Repair Meiotic Cell Cycle Checkpoint Signaling DNA Metabolic Process Regulation Of Cell Cycle Process DNA Damage Response Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Cellular Response To Stress Regulation Of Mitotic Cell Cycle Intracellular Signal Transduction Nucleic Acid Metabolic Process Meiotic DNA Integrity Checkpoint Signaling Nucleobase-containing Compound Metabolic Process Meiotic Recombination Checkpoint Signaling Response To Stress Negative Regulation Of Meiotic Nuclear Division Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Mitotic DNA Replication Checkpoint Signaling Nucleoplasm 3'-5' Exonuclease Activity Signal Transduction Negative Regulation Of Meiotic Cell Cycle Macromolecule Metabolic Process Regulation Of Meiotic Nuclear Division Substantia Nigra Development Exonuclease Activity Mitotic G2/M Transition Checkpoint Nucleotide-excision Repair Regulation Of Meiotic Cell Cycle Damaged DNA Binding Neural Nucleus Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Reproductive Process
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