HUS1B

Gene Name		HUS1 checkpoint homolog b (S. pombe)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Checkpoint Clamp Complex
	Molecular Function
	Biological Process	DNA Damage Checkpoint DNA Repair
Pathways
Drugs
Diseases
GWAS		Aging ( 22773346)
Protein-protein Interactions		4 interactors: HUS1 RAD1 RAD9A RAD9B
Entrez ID		135458
HPRD ID		13722
Ensembl ID		ENSG00000188996
Uniprot IDs		Q8NHY5
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Damage Checkpoint Cell Cycle Checkpoint DNA Replication Cellular Response To Ionizing Radiation DNA Repair Cellular Response To Radiation Response To Ionizing Radiation Cellular Response To DNA Damage Stimulus Cell Cycle Process DNA Metabolic Process Cell Cycle DNA Catabolic Process, Exonucleolytic Cellular Response To Stress Response To Radiation Negative Regulation Of Cell Cycle DNA Catabolic Process Regulation Of Cell Cycle Mitotic Cell Cycle Checkpoint Meiotic Recombination Checkpoint Response To Abiotic Stimulus Response To Stress Negative Regulation Of Mitotic Cell Cycle Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Biosynthetic Process Intra-S DNA Damage Checkpoint DNA Replication Checkpoint Cellular Nitrogen Compound Metabolic Process Aromatic Compound Catabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Meiotic Nuclear Division Mitotic Cell Cycle Process Negative Regulation Of Meiotic Cell Cycle Mitotic Cell Cycle Cellular Response To Stimulus Substantia Nigra Development Regulation Of Meiosis Cellular Macromolecule Catabolic Process Negative Regulation Of DNA Replication Regulation Of Meiotic Cell Cycle Neural Nucleus Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Response To DNA Damage Stimulus Double-strand Break Repair Via Homologous Recombination
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