CHRNB2

Gene Name		cholinergic receptor, nicotinic, beta 2 (neuronal)
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Acetylcholine-gated Channel Complex External Side Of Plasma Membrane Integral Component Of Membrane Cell Junction Postsynaptic Membrane
	Molecular Function	Acetylcholine-activated Cation-selective Channel Activity Drug Binding Ligand-gated Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine Binding Protein Heterodimerization Activity
	Biological Process	Action Potential Conditioned Taste Aversion Response To Hypoxia Ion Transport Calcium Ion Transport Smooth Muscle Contraction Signal Transduction Synaptic Transmission Synaptic Transmission, Cholinergic Visual Perception Sensory Perception Of Sound Learning Memory Locomotory Behavior Associative Learning Visual Learning Regulation Of Dopamine Secretion Sensory Perception Of Pain Vestibulocochlear Nerve Development Optic Nerve Morphogenesis Lateral Geniculate Nucleus Development Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of B Cell Proliferation Regulation Of Synaptic Transmission, Dopaminergic Positive Regulation Of Synaptic Transmission, Dopaminergic Positive Regulation Of Dopamine Secretion Ion Transmembrane Transport Response To Nicotine Behavioral Response To Nicotine Social Behavior Regulation Of Dopamine Metabolic Process B Cell Activation Response To Cocaine Regulation Of Circadian Sleep/wake Cycle, REM Sleep Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Ethanol Negative Regulation Of Action Potential Regulation Of Dendrite Morphogenesis Neurological System Process Cognition Protein Heterooligomerization Membrane Depolarization Regulation Of Synapse Assembly Synaptic Transmission Involved In Micturition Cation Transmembrane Transport
Pathways		Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Acetylcholine Binding And Downstream Events Postsynaptic nicotinic acetylcholine receptors Activation of Nicotinic Acetylcholine Receptors Presynaptic nicotinic acetylcholine receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Highly sodium permeable acetylcholine nicotinic receptors Highly calcium permeable nicotinic acetylcholine receptors Transmission across Chemical Synapses
Drugs		Nicotine Galantamine
Diseases
GWAS
Protein-protein Interactions		3 interactors: CHRNA2 CHRNA4 CRELD2
Entrez ID		1141
HPRD ID		00335
Ensembl ID		ENSG00000160716
Uniprot IDs		P17787 Q5SXY3
PDB IDs		2GVT 2K58 2K59 2KSR 2LM2
Enriched GO Terms of Interacting Partners?		Behavioral Response To Nicotine Synaptic Transmission Synaptic Transmission, Cholinergic Regulation Of Inhibitory Postsynaptic Membrane Potential Cell-cell Signaling Cation Transmembrane Transport Regulation Of Dopamine Secretion Exploration Behavior Cation Transport Membrane Hyperpolarization Ion Transmembrane Transport Response To Nicotine Respiratory Gaseous Exchange Transmembrane Transport Ion Transport Regulation Of Postsynaptic Membrane Potential Action Potential Sensory Perception Of Pain Membrane Depolarization Protein Heterooligomerization Regulation Of Anion Transport Response To Alkaloid B Cell Activation Adult Behavior
Tagcloud ?		300ppm aminobutyric biotin cholinergic dentate deoxynucleotidyl dutp ergic fimbria gabaergic hexachlorophene hilus inputs interneuron interneurons intramyelinic myelin neurogenesis nick nicotinic offspring pnd punctate reelin reversibly septal sgz subgranular vacuolation