KLK8

Gene Name		kallikrein-related peptidase 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding
	Biological Process	Proteolysis Memory Cell Death Response To Wounding Negative Regulation Of Myelination Keratinocyte Proliferation Negative Regulation Of Axon Regeneration Neuron Projection Morphogenesis Regulation Of Synapse Organization Synapse Organization
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: KRTAP10-3 NOTCH2NL RGS2
Entrez ID		11202
HPRD ID		05733
Ensembl ID		ENSG00000129455
Uniprot IDs		O60259
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Relaxation Of Vascular Smooth Muscle Negative Regulation Of Cardiac Muscle Hypertrophy Relaxation Of Smooth Muscle Negative Regulation Of Muscle Hypertrophy Positive Regulation Of Striated Muscle Contraction Relaxation Of Cardiac Muscle Positive Regulation Of Microtubule Polymerization Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Lipase Activity Negative Regulation Of Muscle Contraction Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Regulation Of Cardiac Muscle Hypertrophy Vasodilation Brown Fat Cell Differentiation Regulation Of Smooth Muscle Contraction Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Cardiac Muscle Contraction Negative Regulation Of MAP Kinase Activity Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Polymerization Fat Cell Differentiation Negative Regulation Of Protein Serine/threonine Kinase Activity Notch Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization Regulation Of Muscle Contraction Negative Regulation Of MAPK Cascade Regulation Of Heart Contraction Regulation Of Microtubule-based Process Positive Regulation Of Protein Complex Assembly Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity
Tagcloud ?		adamts adamts5deltacat aggrecan capn2 cartilage col10a1 crlf1 degradome destabilization destabilized dmm dysregulated erosion foxo4 hybridized il11 inhba joints meniscus microdissection mmp3 oa phdla2 postsurgery priorities prss46 ptgs2 sentinel xbp1