TPPP

Gene Name		tubulin polymerization promoting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Tubulin Binding
	Biological Process	Microtubule Bundle Formation Positive Regulation Of Protein Complex Assembly Positive Regulation Of Protein Polymerization Microtubule Polymerization
Pathways
Drugs
Diseases
GWAS		Ulcerative colitis ( 20228799)
Protein-protein Interactions		5 interactors: APP CDK11B GAPDH GSK3B HDAC6
Entrez ID		11076
HPRD ID		18522
Ensembl ID		ENSG00000171368
Uniprot IDs		O94811 Q4L233
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Apoptotic Process Programmed Cell Death Cell Death Death Cellular Protein Modification Process Neuron Apoptotic Process Cellular Response To Heat Neuron Death Regulation Of Growth Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Peptidyl-cysteine S-trans-nitrosylation Hsp90 Deacetylation Regulation Of Proteolysis Cellular Protein Metabolic Process Response To Heat Regulation Of Cellular Protein Metabolic Process Regulation Of Receptor Activity Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Innate Immune Response Regulation Of Protein Binding Regulation Of Gene Expression Negative Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Chaperone-mediated Protein Complex Assembly Synaptic Growth At Neuromuscular Junction Superior Temporal Gyrus Development Polyubiquitinated Misfolded Protein Transport Regulation Of Microtubule-based Process Positive Regulation Of Protein Complex Assembly Re-entry Into Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Negative Regulation Of Neuron Maturation Peptidyl-amino Acid Modification Response To Temperature Stimulus Negative Regulation Of Neuron Differentiation Protein Metabolic Process Regulation Of Gene Expression, Epigenetic Hypermethylation Of CpG Island Negative Regulation Of Hydrogen Peroxide Metabolic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Response To Abiotic Stimulus Peptidyl-cysteine S-nitrosylation Collateral Sprouting Axon Midline Choice Point Recognition Cellular Response To Interleukin-3 Regulation Of Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud ?		anterior compensatory corticospinal counted densitometry diseased emphasized emphasizes harbor horn horns immunolabeling inclusions lcs lcss mbp myelin oligodendrocyte oligodendrocytes oligodendroglia oligodendroglial p25 p62 perineuronal pnogs presentations proteinopathies suggestive tracts