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NPFFR2
Gene Name
neuropeptide FF receptor 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Actin Cytoskeleton
Molecular Function
G-protein Coupled Receptor Activity
Neuropeptide Receptor Activity
Opioid Receptor Binding
Peptide Binding
Biological Process
G-protein Coupled Receptor Signaling Pathway
Neuropeptide Signaling Pathway
Synaptic Transmission
Detection Of Abiotic Stimulus
Cellular Response To Hormone Stimulus
Regulation Of MAPK Cascade
Regulation Of Adenylate Cyclase Activity
Response To Peptide
Regulation Of CAMP-dependent Protein Kinase Activity
Pathways
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Class A/1 (Rhodopsin-like receptors)
Orexin and neuropeptides FF and QRFP bind to their respective receptors
GPCR ligand binding
Metabolic disorders of biological oxidation enzymes
G alpha (q) signalling events
GPCR downstream signaling
Peptide ligand-binding receptors
Gastrin-CREB signalling pathway via PKC and MAPK
Drugs
Diseases
GWAS
Protein-protein Interactions
3 interactors:
HCRT
NPFF
NPY
Entrez ID
10886
HPRD ID
16244
Ensembl ID
ENSG00000056291
Uniprot IDs
A0PJM9
Q9Y5X5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Neuropeptide Signaling Pathway
Regulation Of Response To Food
Regulation Of Appetite
Synaptic Transmission
Regulation Of Neurological System Process
Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Postsynaptic Membrane Potential
Feeding Behavior
Cell-cell Signaling
Membrane Depolarization
G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Blood Pressure
Cytosolic Calcium Ion Homeostasis
Somatostatin Secretion
Vasopressin Secretion
Regulation Of Membrane Potential
Cellular Calcium Ion Homeostasis
Negative Regulation Of Transmission Of Nerve Impulse
Calcium Ion Homeostasis
Blood Circulation
Positive Regulation Of Appetite
Negative Regulation Of Transport
Cellular Metal Ion Homeostasis
Positive Regulation Of Transmission Of Nerve Impulse
Response To Nutrient Levels
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Acute Inflammatory Response To Antigenic Stimulus
Response To Extracellular Stimulus
Metal Ion Homeostasis
Negative Regulation Of Heart Rate
Adult Feeding Behavior
Negative Regulation Of Appetite
Regulation Of Transmission Of Nerve Impulse
Cellular Chemical Homeostasis
Ion Homeostasis
Negative Regulation Of Neurological System Process
Behavior
Regulation Of Secretion
Cell Surface Receptor Signaling Pathway
Cellular Homeostasis
Negative Regulation Of Potassium Ion Transport
Negative Regulation Of Heart Contraction
Regulation Of Sensory Perception Of Pain
Eating Behavior
Chemical Homeostasis
Inflammatory Response To Antigenic Stimulus
Regulation Of Membrane Depolarization
Positive Regulation Of Blood Pressure
Tagcloud
?
attenuate
augmented
beta3
cathepsin
corning
dependently
griess
intbeta3
integrin
metallopeptidase
modulates
mtt
neuropeptide
nfatc1
osteo
osteoclast
osteoclastogenesis
plates
rank
rankl
raw264
resorption
stain
stripwell
tartrate
viability