SPINT2

Gene Name		serine peptidase inhibitor, Kunitz type, 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm Integral Component Of Membrane
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Movement Of Cell Or Subcellular Component Negative Regulation Of Endopeptidase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: APP CTSB HGFAC ITIH2 ITIH3 SUMO4
Entrez ID		10653
HPRD ID		05495
Ensembl ID		ENSG00000167642
Uniprot IDs		O43291
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Hyaluronan Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Proteolysis Synaptic Growth At Neuromuscular Junction Negative Regulation Of Catalytic Activity Collateral Sprouting In Absence Of Injury Negative Regulation Of Cellular Protein Metabolic Process Glycosaminoglycan Metabolic Process Negative Regulation Of Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Catalytic Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Response To Thyroid Hormone Stimulus Extracellular Matrix Organization Extracellular Structure Organization Response To Thyroid Hormone Decidualization Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior
Tagcloud ?		adhesion cd49b cd49d cd49e clonal defective downregulated dysfunctional hematopoiesis hematopoietic hepatocyte herein hgf hsc ineffective kunitz microenvironment msc mscs niche onto pathophysiology progenitors renewal sdf silenced stromal supporting underexpression