CITED2

Gene Name		Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
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Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Histone Acetyltransferase Binding LBD Domain Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Hypoxia Liver Development Outflow Tract Morphogenesis Regulation Of Organ Formation Transcription, DNA-templated Determination Of Left/right Symmetry Heart Development Sex Determination Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell-cell Adhesion Cell Differentiation Negative Regulation Of Cell Migration Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Fluid Shear Stress Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Adrenal Cortex Formation Negative Regulation Of Apoptotic Process Response To Estrogen Positive Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Spleen Development Ventricular Septum Morphogenesis Embryonic Heart Tube Left/right Pattern Formation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Left/right Axis Specification Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Male Gonad Development
Pathways
Drugs
Diseases
GWAS		Blood trace element (Se levels) ( 23720494) HDL cholesterol ( 20686565) Mean corpuscular hemoglobin ( 23263863 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Obesity-related traits ( 23251661) Red blood cell traits ( 23222517)
Protein-protein Interactions		10 interactors: CREBBP EP300 HIF1A LHX2 LHX3 TBP TFAP2A TFAP2B TFAP2C UBC
Entrez ID		10370
HPRD ID		04245
Ensembl ID		ENSG00000164442
Uniprot IDs		D9ZGF1 Q99967
PDB IDs		1P4Q 1R8U
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Tube Development RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Metabolic Process Gene Expression Regulation Of DNA-templated Transcription In Response To Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Cellular Response To Hypoxia Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Cellular Response To Decreased Oxygen Levels Nucleobase-containing Compound Metabolic Process Cellular Response To Oxygen Levels Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Notch Signaling Pathway N-terminal Peptidyl-lysine Acetylation Anatomical Structure Morphogenesis Retina Development In Camera-type Eye Nitrogen Compound Metabolic Process Forebrain Development Pattern Specification Process Organ Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Epithelium Development Germ-line Stem Cell Maintenance
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