RGS19

Gene Name		regulator of G-protein signaling 19
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Heterotrimeric G-protein Complex Plasma Membrane Brush Border Membrane Clathrin-coated Vesicle
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activator Activity Protein Binding
	Biological Process	Autophagy G-protein Coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK G alpha (z) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-protein Interactions		15 interactors: CSNK2A1 CSNK2A2 GDE1 GIPC1 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ MAPK1 MAPK6 OPRL1 OSTM1 PRKCA TGFBR1
Entrez ID		10287
HPRD ID		05461
Ensembl ID		ENSG00000171700
Uniprot IDs		B4DP94 P49795
PDB IDs		1CMZ
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Surface Receptor Signaling Pathway Cell Cycle Synaptic Transmission Platelet Activation G-protein Coupled Receptor Signaling Pathway Signal Transduction Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Signaling Cell-cell Signaling Cell Communication Negative Regulation Of CAMP Biosynthetic Process Negative Regulation Of CAMP Metabolic Process Wound Healing Negative Regulation Of Nucleotide Metabolic Process Cell Activation Response To Wounding Peptidyl-threonine Phosphorylation Cellular Response To Stimulus Blood Coagulation Hemostasis Regulation Of Adenylate Cyclase Activity Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Activation Of MAPKK Activity Regulation Of Cyclase Activity Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Body Fluid Levels Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Response To Stimulus Negative Regulation Of Protein Catabolic Process Peptidyl-serine Phosphorylation Locomotion Positive Regulation Of Signal Transduction Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Phosphorylation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Proliferation Positive Regulation Of MAPK Cascade Movement Of Cell Or Subcellular Component Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Proteasomal Protein Catabolic Process Apoptotic Process Programmed Cell Death Mitotic Spindle Checkpoint
Tagcloud ?		accelerating adenylate c6 cyclase dampen depressant galphai galphai2 gap gaps go gpcr gpcrs gtpase hairpin ht1a implicating insensitive medications mood neuroblastoma postsynaptic prefrontal raphe shrna sy5y synergy viable