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SIGMAR1

Description sigma non-opioid intracellular receptor 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Nuclear Envelope
  • Nuclear Inner Membrane
  • Nuclear Outer Membrane
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Lipid Droplet
  • Cytosol
  • Plasma Membrane
  • Postsynaptic Density
  • Membrane
  • Growth Cone
  • Cytoplasmic Vesicle
  • Cell Projection
  • Synapse
  • Postsynaptic Membrane
  • Anchoring Junction
  • Postsynapse
  • Postsynaptic Density Membrane
  • Glutamatergic Synapse
Molecular Function
  • G Protein-coupled Opioid Receptor Activity
  • Protein Binding
  • Signaling Receptor Activity
  • Identical Protein Binding
Biological Process
  • Lipid Transport
  • Nervous System Development
  • G Protein-coupled Opioid Receptor Signaling Pathway
  • Regulation Of Neuron Apoptotic Process
  • Protein Homotrimerization
  • Regulation Of Postsynapse Assembly
Pathways
  • Potential therapeutics for SARS
Drugs
  • Amitriptyline
  • Remoxipride
  • Haloperidol
  • Dextromethorphan
  • Nortriptyline
  • Fenfluramine
  • Pentazocine
  • Naltrexone
  • Cocaine
  • Hydrocodone
  • Sertraline
  • Dimethyltryptamine
  • Prasterone
  • Phencyclidine
  • Pimavanserin
  • Noscapine
  • Captodiame
  • Pentoxyverine
Diseases
GWAS
Novel Interacting Genes 10 novel interacting genes: DCAF12 DNAJB5 GNE NFX1 PHF24 RECK RUSC2 SPAG8 SPINK4 VCP
Interacting Genes 5 interacting genes: ANK2 GHSR ITPR3 PDZD11 SRI
Entrez ID 10280
HPRD ID 03580
Ensembl ID ENSG00000147955
Uniprot IDs A0A7P0T9D5 A0A7P0Z4C2 B4DR71 Q99720
PDB IDs 5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025