FSTL3

Gene Name		follistatin-like 3 (secreted glycoprotein)
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Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Golgi Apparatus Secretory Granule Neuron Projection Terminus
	Molecular Function	Fibronectin Binding Protein Binding Activin Binding
	Biological Process	Ossification Kidney Development Hematopoietic Progenitor Cell Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spermatogenesis Male Gonad Development Positive Regulation Of Cell-cell Adhesion Lung Development Adrenal Gland Development Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Metal Ion Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Pathways		Antagonism of Activin by Follistatin Signaling by Activin
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: ADAM12 FN1 INHBA MSTN SMAD4
Entrez ID		10272
HPRD ID		05632
Ensembl ID		ENSG00000070404
Uniprot IDs		O95633
PDB IDs		2KCX 3B4V 3SEK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Endoderm Development Regulation Of Growth Gastrulation Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Growth Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Endodermal Cell Differentiation Regulation Of Cell Growth Positive Regulation Of Protein Metabolic Process Endoderm Formation Cell Differentiation Growth Regulation Of Cell Differentiation Tissue Development Cell Development Ovulation Cycle Process Embryonic Morphogenesis Palate Development Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Myoblast Proliferation Negative Regulation Of Skeletal Muscle Tissue Growth Negative Regulation Of Cell Proliferation Regulation Of Cellular Protein Metabolic Process Ovulation Cycle Positive Regulation Of Protein Phosphorylation Negative Regulation Of Cell Differentiation Formation Of Primary Germ Layer Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Metabolic Process Mesoderm Development Anatomical Structure Development Progesterone Secretion Nephrogenic Mesenchyme Morphogenesis Negative Regulation Of Satellite Cell Differentiation Negative Regulation Of Skeletal Muscle Satellite Cell Proliferation Negative Regulation Of Cell Growth Positive Regulation Of Cell Differentiation Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Phosphorylation Anatomical Structure Morphogenesis Positive Regulation Of Protein Modification Process Cellular Response To Transforming Growth Factor Beta Stimulus Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Response To Transforming Growth Factor Beta
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