ARFRP1

Description		ARF related protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Gastrulation Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport
Pathways		Retrograde transport at the Trans-Golgi-Network Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 30604766) Inflammatory bowel disease ( 28067908) Platelet count ( 32888494) Prostate cancer ( 23535732) Refractive error ( 32231278) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) Ulcerative colitis ( 28067908)
Novel Interacting Genes		1 novel interacting genes: DNAJB13
Interacting Genes		6 interacting genes: AP1G1 AP1M1 CYTH1 GLP1R SMAD4 VANGL2
Entrez ID		10139
HPRD ID		05264
Ensembl ID		ENSG00000101246
Uniprot IDs		A0A384P5U7 B7ZKY8 Q13795
PDB IDs
Enriched GO Terms of Interacting Partners?		Endosome To Melanosome Transport AP-1 Adaptor Complex Clathrin Adaptor Activity Melanosome Assembly Platelet Dense Granule Organization Clathrin-coated Vesicle Membrane Melanosome Organization Pigment Granule Organization Collagen Binding Clathrin-coated Vesicle Secretory Granule Organization Glucagon-like Peptide 1 Receptor Activity Muscle Tissue Morphogenesis Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Synaptic Vesicle Budding From Endosome Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Orthogonal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Establishment Of Planar Polarity Involved In Neural Tube Closure Cell Pole Cell Migration Involved In Kidney Development Lateral Sprouting Involved In Lung Morphogenesis Planar Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Trans-Golgi Network Membrane Intracellular Protein Transport Glucagon Receptor Activity Activin Responsive Factor Complex Left Ventricular Cardiac Muscle Tissue Morphogenesis Metanephric Mesenchyme Morphogenesis Serotonergic Neuron Axon Guidance Convergent Extension Involved In Neural Plate Elongation Dopaminergic Neuron Axon Guidance Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Basolateral Protein Secretion Golgi Membrane Positive Regulation Of Natural Killer Cell Degranulation Cytoplasmic Vesicle Membrane Response To Psychosocial Stress Positive Regulation Of Luteinizing Hormone Secretion Anterior/posterior Pattern Specification Sulfate Binding Endocardial Cell Differentiation Establishment Or Maintenance Of Cell Polarity Apical Cytoplasm Convergent Extension Involved In Organogenesis Establishment Of Body Hair Planar Orientation Establishment Of Planar Polarity Of Embryonic Epithelium Axonemal Central Apparatus Assembly
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