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OCLN
Gene Name
occludin
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Plasma Membrane
Cell-cell Junction
Tight Junction
Integral Component Of Membrane
Apical Plasma Membrane
Apicolateral Plasma Membrane
Cell Junction
Endocytic Vesicle
Cytoplasmic Vesicle
Molecular Function
Structural Molecule Activity
Protein Binding
Thiopurine S-methyltransferase Activity
Protein Domain Specific Binding
Biological Process
Protein Complex Assembly
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Methylation
Cell-cell Junction Organization
S-adenosylhomocysteine Metabolic Process
S-adenosylmethionine Metabolic Process
Tight Junction Assembly
Pathways
Apoptotic cleavage of cell adhesion proteins
Apoptotic cleavage of cellular proteins
Programmed Cell Death
Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-protein Interactions
4 interactors:
CLEC7A
SYNE4
TJP2
TNFAIP3
Entrez ID
100506658
HPRD ID
Ensembl ID
ENSG00000197822
Uniprot IDs
A8K3T2
Q16625
PDB IDs
1WPA
1XAW
3G7C
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway
Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Negative Regulation Of Toll-like Receptor 5 Signaling Pathway
Negative Regulation Of CD40 Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
Negative Regulation Of Osteoclast Proliferation
Tolerance Induction To Lipopolysaccharide
Positive Regulation Of Innate Immune Response
Carbohydrate Mediated Signaling
Regulation Of CD40 Signaling Pathway
Regulation Of Vascular Wound Healing
Positive Regulation Of Hepatocyte Proliferation
Negative Regulation Of Chronic Inflammatory Response
Regulation Of Innate Immune Response
Establishment Of Epithelial Cell Apical/basal Polarity
Negative Regulation Of Toll-like Receptor 2 Signaling Pathway
Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway
B-1 B Cell Homeostasis
Establishment Of Endothelial Intestinal Barrier
Establishment Of Apical/basal Cell Polarity
Polarized Epithelial Cell Differentiation
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Tolerance Induction
Regulation Of Hepatocyte Proliferation
Protein K11-linked Deubiquitination
Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Establishment Of Monopolar Cell Polarity
Regulation Of Chronic Inflammatory Response
Inflammatory Response
Negative Regulation Of Bone Resorption
Negative Regulation Of Interleukin-1 Beta Production
Regulation Of Germinal Center Formation
Immune Response-regulating Signaling Pathway
Negative Regulation Of Bone Remodeling
Negative Regulation Of Tissue Remodeling
Response To Muramyl Dipeptide
Protein K48-linked Deubiquitination
Phagocytosis, Recognition
Protein K63-linked Deubiquitination
Establishment Of Epithelial Cell Polarity
Epithelial Cell Differentiation
Negative Regulation Of Interleukin-2 Production
Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Establishment Of Protein Localization To Vacuole
Defense Response To Protozoan
Tagcloud
?
accordingly
ap4
besides
bioinformatic
cadherin
cd44
cdh1
claudins
concomitantly
conversely
crc
displays
ectopic
emt
fn1
helix
hundreds
imply
invasion
lgr5
mesenchymal
myc
presumably
repressed
snail
stemness
tfap4
transition
vim