FBH1 and ZDHHC17

Number of citations of the paper that reports this interaction (PubMedID 24705354)
111

Data Source:
BioGRID (two hybrid)

		FBH1	ZDHHC17
Description		F-box DNA helicase 1	zDHHC palmitoyltransferase 17
Image
GO Annotations	Cellular Component	Chromatin Nucleus Chromosome SCF Ubiquitin Ligase Complex	Golgi Membrane Golgi Apparatus Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Golgi-associated Vesicle Membrane Cytoplasmic Vesicle Presynaptic Membrane Cell Projection Synapse Glutamatergic Synapse Perforant Pathway To Dendrate Granule Cell Synapse Postsynaptic Golgi Apparatus
	Molecular Function	Nucleotide Binding DNA Binding DNA Helicase Activity Double-stranded DNA Binding Single-stranded DNA Binding Helicase Activity Protein Binding ATP Binding DNA Translocase Activity Hydrolase Activity Isomerase Activity ATP Hydrolysis Activity 3'-5' DNA Helicase Activity	Signaling Receptor Binding Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding Protein-cysteine S-stearoyltransferase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Protein Phosphorylation DNA Repair DNA Catabolic Process DNA Damage Response Protein Ubiquitination Replication Fork Processing Response To Intra-S DNA Damage Checkpoint Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Double-strand Break Repair Via Homologous Recombination	Axonogenesis Protein Palmitoylation Lipoprotein Transport Regulation Of Programmed Cell Death Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission
Pathways
Drugs
Diseases
GWAS			Mean arterial pressure x educational attainment (some college) interaction (2df) ( 32372009) Metabolite levels ( 23823483) Visceral fat ( 30942860)
Interacting Genes		12 interacting genes: CUL1 DSCR9 ESR1 PCNA PIM2 RAD51 RBX1 RNF20 RPL13A SKP1 UBC ZDHHC17	194 interacting genes: ABCG4 ACTR1B ADD1 AHDC1 AIDA AK3 ALKBH3 ANKRD50 ANXA11 APBB1IP ARFGAP3 ASF1A ASIC4 BCAS3 BEX2 BTF3 C1orf216 C20orf141 CBS CCDC120 CCDC7 CCNE2 CDSN CENPBD2P CHMP1A CIB1 CLRN3 CNDP2 CNKSR1 COG3 CSTA CTCFL CTHRC1 DALRD3 DELE1 DIXDC1 DLG4 DLK1 DR1 DTX3 E2F8 EDRF1 EEF1G ERCC6L EVL EXOSC9 EYA3 FAM9A FBH1 FOXD4L6 FTL FUT2 FUT9 GABPB1 GABPB2 GATA1 GOLPH3L GPR135 GRB10 GUSBP3 H2AP H2BC9 H3C10 HBG1 HECTD3 HLA-A HLA-DRB1 HMBS HOXA3 HS1BP3 HTT IFT20 IFT57 INPP5D JMJD7-PLA2G4B KHDC4 KIAA0408 KNSTRN KRAS KRT17 KRT8P12 KRTAP11-1 KRTAP9-2 LCA5L LCMT1P1 LGALS9C LIN28A LMAN2L LNCRI LRRC45 LY6G6C MANF MAP2K4 MAP3K19 MIIP MLH3 MRFAP1 MRFAP1L1 MSANTD3 MSRB2 MYBPHL MYOZ2 NAP1L1 NCBP1 NEBL NFATC2IP NFYC NIFK NPFF ODF2 OFCC1 OTUD7B OTX2 PABIR3 PBRM1 PDE4DIP PDZK1IP1 PHF5A PLEKHB1 PPP1R21 PPTC7 PRMT5 PTMA QRICH1 RAB39B RAD51 RANGRF RAP1B RBM5 RCAN3 RIC8A RNF20 RNF38 RSBN1L RUBCNL SCNM1 SEMA4G SF3A3 SHOX2 SKA3 SLC1A3 SLC25A31 SLC9A9 SLX9 SMARCB1 SNAP25 SOX14 SP2 SPRY3 SPRY4 SREBF2 SRSF4 STK25 STN1 SUMF2 SYT1 TEAD1 THAP7 TIGD1 TMC6 TMCC1 TMEM115 TMEM186 TMTC1 TNFAIP1 TNFSF10 TOX TPGS2 TTC23 TTLL7 TUT7 TXNDC12 TXNDC15 UBAC1 UBE2K USP18 USP32 VN1R10P VSX2 WAC WDR20 YIF1A YTHDF3 ZCCHC17 ZFC3H1 ZFP2 ZFP36 ZFYVE19 ZNF333 ZNF341 ZNF597 ZNF624 ZNF667-AS1 ZSCAN9
Entrez ID		84893	23390
HPRD ID		06243	09697
Ensembl ID		ENSG00000134452	ENSG00000186908
Uniprot IDs		B3KV95 F6UZG9 Q2TAK1 Q8NFZ0	A8KA01 Q8IUH5
PDB IDs		8F5Q	3EU9 5W7I 5W7J
Enriched GO Terms of Interacting Partners?		Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Epithelial Cell Apoptotic Process Regulation Of Canonical NF-kappaB Signal Transduction Cul7-RING Ubiquitin Ligase Complex Macromolecule Metabolic Process Protein Monoubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process SCF Ubiquitin Ligase Complex Ubiquitin Ligase Complex Scaffold Activity Positive Regulation Of Canonical NF-kappaB Signal Transduction Modification-dependent Protein Catabolic Process Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination Protein Modification Process Protein Ubiquitination Negative Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin Protein Ligase Binding Cullin-RING Ubiquitin Ligase Complex Protein K48-linked Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation DNA Polymerase Binding Cullin Family Protein Binding Mitotic Cell Cycle Phase Transition Post-translational Protein Modification Cell Cycle Phase Transition Protein Metabolic Process Cellular Response To Radiation Positive Regulation Of Autophagy Regulation Of Programmed Cell Death Chromatin Binding Nuclear Estrogen Receptor Binding Replication Fork Processing Cellular Response To Oxidative Stress Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Male Germ Cell Nucleus PCNA Complex Replisome Response To Glucoside Perforant Pathway To Dendrate Granule Cell Synapse Negative Regulation Of Formation Of Translation Preinitiation Complex Histone H2B C-terminal K Residue Ubiquitin Ligase Activity Cellular Response To Chemical Stress Proteolysis Lysosome Organization TORC1 Signaling Negative Regulation Of TORC1 Signaling Catabolic Process	Protein Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?