CHAF1B and ASF1A

Number of citations of the paper that reports this interaction (PubMedID 11897662)
21

Data Source:
HPRD (in vivo)

		CHAF1B	ASF1A
Description		chromatin assembly factor 1 subunit B	anti-silencing function 1A histone chaperone
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex	Chromatin Nucleus Nucleoplasm Chromosome Protein-containing Complex Site Of Double-strand Break
	Molecular Function	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding	Chromatin Binding Protein Binding Histone Binding Histone Chaperone Activity
	Biological Process	DNA Replication DNA Repair Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly DNA Damage Response	Double-strand Break Repair Via Homologous Recombination Osteoblast Differentiation DNA Repair Chromatin Organization Nucleosome Assembly DNA Replication-dependent Chromatin Assembly DNA Damage Response Replication Fork Processing Muscle Cell Differentiation Protein Localization To Chromatin DNA Repair-dependent Chromatin Remodeling
Pathways			Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)	Mean platelet volume ( 32888494) Multiple sclerosis ( 31604244) QT interval ( 19305408)
Interacting Genes		18 interacting genes: APP ASF1A ASF1B CBR1 CDK1 CDK2 CHAF1A CUX1 H3-4 H3C6 MAL2 PGM1 PLEKHH1 PRELP RBBP4 SETD4 SUMO2 ZNF879	32 interacting genes: ASF1B CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4C1 H4C11 H4C12 H4C13 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HIRA HTATIP2 MCM2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17
Entrez ID		8208	25842
HPRD ID		03147	16459
Ensembl ID		ENSG00000159259	ENSG00000111875
Uniprot IDs		Q13112	Q9Y294
PDB IDs		7Y5K 7Y5L 7Y5O 7Y5U 7Y5V 7Y60 7Y61 8IQF 8IQG 8J6S 8J6T	1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H 6ZUF 7LNY 7LO0 7V6Q 8BV1 8CJ1 8CJ2 8CJ3 8Z50
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Chromatin Assembly Chromatin Remodeling Nucleosome Assembly Chromatin Organization Nucleosome Organization Protein-DNA Complex Assembly Cyclin-dependent Protein Kinase Activity CAF-1 Complex DNA Replication Histone Kinase Activity Protein-containing Complex Assembly Chromosome, Telomeric Region Protein-containing Complex Organization Histone Chaperone Activity Protein-containing Complex DNA Repair Cellular Component Assembly Cyclin-dependent Protein Serine/threonine Kinase Activity Cyclin Binding Response To Copper Ion Extracellular Exosome Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Prostaglandin E2 9-reductase Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity DNA Metabolic Process Pronuclear Fusion DNA Damage Response Positive Regulation Of DNA Replication Cyclin-dependent Protein Kinase Holoenzyme Complex Histone Binding Chromatin Binding G2/M Transition Of Mitotic Cell Cycle Acetylcholine Receptor Activator Activity Regulation Of Transcription By RNA Polymerase II Lipoprotein Particle Positive Regulation Of Protein Import 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity S-nitrosoglutathione Reductase (NADPH) Activity Cell Cycle G2/M Phase Transition Mitotic DNA-templated DNA Replication Cyclin B1-CDK1 Complex Cyclin A1-CDK1 Complex Cyclin A2-CDK1 Complex Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex	Nucleosome Assembly Nucleosome Organization Protein-DNA Complex Assembly CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Structural Constituent Of Chromatin Nucleosome Regulation Of Megakaryocyte Differentiation Protein Localization To Chromosome, Centromeric Region Chromatin Organization Telomere Organization Chromatin Remodeling Chromosome, Telomeric Region Protein Localization To Chromatin Protein Heterodimerization Activity Negative Regulation Of Myeloid Cell Differentiation Protein Localization To Chromosome Protein-containing Complex Assembly Protein-containing Complex Chromosome Organization Protein-containing Complex Organization Chromosome Regulation Of Myeloid Cell Differentiation Cellular Component Assembly Regulation Of Hemopoiesis Extracellular Exosome Protein Localization To Organelle Nucleoplasm Negative Regulation Of Cell Differentiation DNA Binding DNA Replication-dependent Chromatin Assembly Regulation Of Cell Development Negative Regulation Of Developmental Process Intracellular Protein Localization Extracellular Region Organelle Organization RNA Binding Regulation Of Cell Differentiation Nucleus Regulation Of Multicellular Organismal Development Regulation Of Immune System Process CAF-1 Complex Regulation Of Developmental Process Histone Binding Protein Phosphorylation Protein Binding DNA Damage Response Phosphorylation RNA Polymerase II Core Promoter Sequence-specific DNA Binding
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