FCRL2 and ZDHHC22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FCRL2	ZDHHC22
Description		Fc receptor like 2	zDHHC palmitoyltransferase 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Protein Phosphatase Binding Signaling Adaptor Activity	Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Immune Response Cell Surface Receptor Signaling Pathway Cell-cell Signaling	Protein Targeting To Membrane Protein Palmitoylation Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Neurological blood protein biomarker levels ( 31320639) smoking initiation in schizophrenia ( 33691233)	Cerebrospinal P-tau181p levels ( 28247064) Large artery stroke ( 24262325) Smoking status (ever vs never smokers) ( 30643258) Sweet taste preference ( 32572145)
Interacting Genes		5 interacting genes: JAGN1 MAL NCK2 PLP1 ZDHHC22	15 interacting genes: CD79A CLEC4D CLSTN3 CREB3L1 FCRL2 FNDC9 GPX8 LDLRAD4 PROX2 PVR RPRM TMEM14B TMEM86B TMEM88 TRIM59
Entrez ID		79368	283576
HPRD ID		07351	12655
Ensembl ID		ENSG00000132704	ENSG00000177108
Uniprot IDs		B4DVJ9 B4E0W2 Q96LA5	Q8N966
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Myelin Sheath Central Nervous System Myelination Protein Insertion Into Plasma Membrane Myelination Axon Ensheathment Endoplasmic Reticulum Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Positive Regulation Of Apoptotic Signaling Pathway Membrane Raft Polarization Protein Localization To Paranode Region Of Axon Establishment Of Protein Localization To Membrane Peptidase Activator Activity Involved In Apoptotic Process Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Granulocyte Colony-stimulating Factor Signaling Pathway Membrane Raft Distribution Membrane Raft Localization Signal Complex Assembly Response To Endoplasmic Reticulum Stress Positive Regulation Of Translation In Response To Stress Neutrophil Differentiation Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Protein Localization To Axon Schmidt-Lanterman Incisure Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of PERK-mediated Unfolded Protein Response Establishment Of Protein Localization Immunological Synapse Formation Apical Protein Localization Dendritic Spine Development Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Apoptotic Signaling Pathway Astrocyte Development Insulin Metabolic Process Protein Palmitoylation	Membrane
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