ZDHHC22 and PROX2

		ZDHHC22	PROX2
Description		zDHHC palmitoyltransferase 22	prospero homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane	Chromatin Nucleus Cytoplasm
	Molecular Function	Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding
	Biological Process	Protein Targeting To Membrane Protein Palmitoylation Protein Localization To Plasma Membrane	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Pancreas Development Tube Development Cell Fate Commitment Positive Regulation Of Cell Cycle Anatomical Structure Formation Involved In Morphogenesis Embryonic Retina Morphogenesis In Camera-type Eye Lymphatic Endothelial Cell Differentiation Lens Fiber Cell Morphogenesis Hepatocyte Differentiation
Pathways
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Large artery stroke ( 24262325) Smoking status (ever vs never smokers) ( 30643258) Sweet taste preference ( 32572145)	Depression ( 29700475) Gastroesophageal reflux disease ( 34187846) Monocyte count ( 32888494) Mood instability ( 29187730) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965) Parental longevity (father's attained age) ( 29227965) Total cholesterol levels ( 29083408)
Interacting Genes		15 interacting genes: CD79A CLEC4D CLSTN3 CREB3L1 FCRL2 FNDC9 GPX8 LDLRAD4 PROX2 PVR RPRM TMEM14B TMEM86B TMEM88 TRIM59	6 interacting genes: ISM2 LRRC74A SAMD15 SLIRP-OT1 TMED8 ZDHHC22
Entrez ID		283576	283571
HPRD ID		12655	19081
Ensembl ID		ENSG00000177108	ENSG00000119608
Uniprot IDs		Q8N966	G3V3G0 Q3B8N5
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane
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