ZDHHC22 and CLSTN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZDHHC22	CLSTN3
Description		zDHHC palmitoyltransferase 22	calsyntenin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Plasma Membrane Cell Surface Postsynaptic Density Membrane Dendrite Protein-containing Complex Cell Projection Organelle Membrane Contact Site Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Enzyme Inhibitor Activity Calcium Ion Binding Protein Binding Neurexin Family Protein Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Protein Targeting To Membrane Protein Palmitoylation Protein Localization To Plasma Membrane	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Protein Secretion Negative Regulation Of Lipid Storage L-ascorbic Acid Metabolic Process Synaptic Transmission, Glutamatergic Positive Regulation Of Synaptic Transmission Positive Regulation Of Lipid Catabolic Process Synaptic Transmission, GABAergic Regulation Of Synapse Assembly Positive Regulation Of Synapse Assembly Sympathetic Neuron Projection Extension Cell-cell Adhesion Cold-induced Thermogenesis Lipid Droplet Fusion Negative Regulation Of Lipid Droplet Fusion Positive Regulation Of Protein Localization To Synapse Excitatory Synapse Assembly Inhibitory Synapse Assembly Regulation Of Excitatory Synapse Assembly Negative Regulation Of Excitatory Synapse Assembly Regulation Of Presynapse Assembly Positive Regulation Of Inhibitory Synapse Assembly Adaptive Thermogenesis
Pathways
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Large artery stroke ( 24262325) Smoking status (ever vs never smokers) ( 30643258) Sweet taste preference ( 32572145)	Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Schizophrenia ( 30285260)
Interacting Genes		15 interacting genes: CD79A CLEC4D CLSTN3 CREB3L1 FCRL2 FNDC9 GPX8 LDLRAD4 PROX2 PVR RPRM TMEM14B TMEM86B TMEM88 TRIM59	12 interacting genes: APBA2 CMTM7 MAL NKG7 OLFM4 PGAP2 RSPH1 TMEM107 TMEM54 TMEM97 TRAM1L1 ZDHHC22
Entrez ID		283576	9746
HPRD ID		12655	16725
Ensembl ID		ENSG00000177108	ENSG00000139182
Uniprot IDs		Q8N966	Q9BQT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane
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