TFF1 and TRAPPC10

		TFF1	TRAPPC10
Description		trefoil factor 1	trafficking protein particle complex subunit 10
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Golgi Apparatus Cytosol TRAPP Complex TRAPPII Protein Complex
	Molecular Function	Protein Binding Growth Factor Activity	Protein Binding
	Biological Process	Carbohydrate Metabolic Process Signal Transduction Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Response To Iron Ion Cell Differentiation Maintenance Of Gastrointestinal Epithelium Response To Immobilization Stress Response To Peptide Hormone	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport Early Endosome To Golgi Transport Golgi Vesicle Transport Vesicle Tethering
Pathways		Estrogen-dependent gene expression	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		Raloxifene Afimoxifene
Diseases
GWAS		Blood protein levels ( 30072576) Pancreatic cancer ( 22158540)
Interacting Genes		21 interacting genes: AKT1 APC ATM BTN3A1 BTNL8 CD300LD ESR2 FCRL4 FGFR2 GKN2 MUC6 RAD51 SGTB SIGLEC8 TRAPPC10 TSG101 UBQLN1 UBQLN4 VSNL1 XRCC3 ZNF250	15 interacting genes: GET1 SLC19A1 SUMO3 TFF1 TFF2 TFF3 TMPRSS2 TRAPPC12 TRAPPC3L TRAPPC6A TRAPPC6B TRAPPC8 TRPM2 U2AF1 UBE2G2
Entrez ID		7031	7109
HPRD ID		00219	03656
Ensembl ID		ENSG00000160182	ENSG00000160218
Uniprot IDs		P04155	P48553
PDB IDs		1HI7 1PS2 6V1D
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Mitotic Sister Chromatid Separation Regulation Of Cell Cycle Phase Transition Proteolysis Involved In Protein Catabolic Process Regulation Of Macroautophagy Response To Alcohol Regulation Of Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Separation Regulation Of Double-strand Break Repair Via Homologous Recombination Telomere Maintenance ATP-dependent DNA Damage Sensor Activity Telomere Maintenance Via Recombination Mitotic Recombination Regulation Of Sister Chromatid Segregation Cellular Response To Stress Cellular Response To Decreased Oxygen Levels Protein Autophosphorylation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cellular Response To Stress Identical Protein Binding Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Chromosome Segregation Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Nuclear Division Regulation Of Mitotic Nuclear Division Response To X-ray Cellular Response To Gamma Radiation Regulation Of Double-strand Break Repair Recombinational Repair Autophagy Reciprocal Meiotic Recombination Telomere Organization Regulation Of DNA Recombination Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Immune Response-activating Signaling Pathway Cellular Response To Oxygen Levels Negative Regulation Of Macroautophagy Regulation Of Protein Catabolic Process Regulation Of Autophagy Macroautophagy Homologous Recombination Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Macromolecule Catabolic Process Regulation Of TRNA Methylation Negative Regulation Of Mitotic Nuclear Division Meiosis I	TRAPP Complex Vesicle Tethering Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport TRAPPIII Protein Complex Maintenance Of Gastrointestinal Epithelium COPII Vesicle Coating Golgi Vesicle Transport Epithelial Structure Maintenance Digestive System Process Vesicle Organization Anatomical Structure Homeostasis Tissue Homeostasis Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Multicellular Organismal-level Homeostasis CXCR4 Chemokine Receptor Binding Mono-ADP-D-ribose Binding Cis-Golgi Network Cellular Localization Establishment Of Localization In Cell Folate Import Across Plasma Membrane 2',3'-cyclic GMP-AMP Binding Cyclic-GMP-AMP Transmembrane Transporter Activity Cellular Response To Temperature Stimulus Positive Regulation Of Protein Localization To Kinetochore Folic Acid Transmembrane Transporter Activity Folate Transmembrane Transport Entry Receptor-mediated Virion Attachment To Host Cell GET Complex Vesicle-mediated Transport Intracellular Transport Regulation Of Kinetochore Assembly Negative Regulation Of Gastric Acid Secretion Viral Translation ADP-ribose Diphosphatase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?