TRAPPC10 and SLC19A1

		TRAPPC10	SLC19A1
Description		trafficking protein particle complex subunit 10	solute carrier family 19 member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol TRAPP Complex TRAPPII Protein Complex	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Brush Border Membrane
	Molecular Function	Protein Binding	Protein Binding Folic Acid Binding Organic Anion Transmembrane Transporter Activity Folic Acid Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Antiporter Activity Methotrexate Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity 2',3'-cyclic GMP-AMP Binding Vitamin Transmembrane Transporter Activity Cyclic-GMP-AMP Transmembrane Transporter Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport Early Endosome To Golgi Transport Golgi Vesicle Transport Vesicle Tethering	Xenobiotic Transmembrane Transport Female Pregnancy Response To Xenobiotic Stimulus Response To Toxic Substance Organic Anion Transport Folic Acid Transport Folic Acid Metabolic Process Vitamin Transport Methotrexate Transport Monoatomic Anion Transmembrane Transport Folate Transmembrane Transport Cyclic-GMP-AMP Transmembrane Import Across Plasma Membrane Positive Regulation Of CGAS/STING Signaling Pathway Transport Across Blood-brain Barrier Folate Import Across Plasma Membrane
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Metabolism of folate and pterines
Drugs
Diseases
GWAS			Ankle injury ( 28957384)
Interacting Genes		15 interacting genes: GET1 SLC19A1 SUMO3 TFF1 TFF2 TFF3 TMPRSS2 TRAPPC12 TRAPPC3L TRAPPC6A TRAPPC6B TRAPPC8 TRPM2 U2AF1 UBE2G2	3 interacting genes: KRT26 SH3BGR TRAPPC10
Entrez ID		7109	6573
HPRD ID		03656	02691
Ensembl ID		ENSG00000160218	ENSG00000173638
Uniprot IDs		P48553	P41440
PDB IDs			7TX6 7TX7 7XPZ 7XQ0 7XQ1 7XQ2 7XTK 8DEP 8GOE 8GOF 8HII 8HIJ 8HIK 9JOZ 9JRI 9JRK 9JRL 9JRM 9JRN
Enriched GO Terms of Interacting Partners?		TRAPP Complex Vesicle Tethering Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport TRAPPIII Protein Complex Maintenance Of Gastrointestinal Epithelium COPII Vesicle Coating Golgi Vesicle Transport Epithelial Structure Maintenance Digestive System Process Vesicle Organization Anatomical Structure Homeostasis Tissue Homeostasis Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Multicellular Organismal-level Homeostasis CXCR4 Chemokine Receptor Binding Mono-ADP-D-ribose Binding Cis-Golgi Network Cellular Localization Establishment Of Localization In Cell Folate Import Across Plasma Membrane 2',3'-cyclic GMP-AMP Binding Cyclic-GMP-AMP Transmembrane Transporter Activity Cellular Response To Temperature Stimulus Positive Regulation Of Protein Localization To Kinetochore Folic Acid Transmembrane Transporter Activity Folate Transmembrane Transport Entry Receptor-mediated Virion Attachment To Host Cell GET Complex Vesicle-mediated Transport Intracellular Transport Regulation Of Kinetochore Assembly Negative Regulation Of Gastric Acid Secretion Viral Translation ADP-ribose Diphosphatase Activity	TRAPPII Protein Complex TRAPP Complex Early Endosome To Golgi Transport
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