NPS and MMP21

		NPS	MMP21
Description		neuropeptide S	matrix metallopeptidase 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Synapse	Extracellular Region Extracellular Matrix
	Molecular Function		Metalloendopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Neuropeptide Signaling Pathway Visual Learning Positive Regulation Of Circadian Sleep/wake Cycle, Wakefulness Positive Regulation Of Synaptic Transmission, GABAergic Synaptic Transmission, Glutamatergic Positive Regulation Of Action Potential Positive Regulation Of Synaptic Transmission, Glutamatergic	Hematopoietic Progenitor Cell Differentiation Proteolysis Determination Of Left/right Symmetry Extracellular Matrix Organization Collagen Catabolic Process Coronary Vasculature Development Determination Of Heart Left/right Asymmetry
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events
Drugs			Marimastat
Diseases
GWAS		Chronotype ( 30696823)	Metabolite levels ( 23823483)
Interacting Genes		1 interacting genes: MMP21	4 interacting genes: CLRN3 DOCK1 FOXI2 NPS
Entrez ID		594857	118856
HPRD ID		19031	07003
Ensembl ID		ENSG00000214285	ENSG00000154485
Uniprot IDs		P0C0P6	Q8N119
PDB IDs
Enriched GO Terms of Interacting Partners?		Determination Of Heart Left/right Asymmetry Collagen Metabolic Process Collagen Catabolic Process Determination Of Bilateral Symmetry Hematopoietic Progenitor Cell Differentiation Metalloendopeptidase Activity Coronary Vasculature Development Determination Of Left/right Symmetry Metallopeptidase Activity Blood Vessel Development Extracellular Structure Organization Extracellular Matrix Organization
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