MMP21 and CLRN3

		MMP21	CLRN3
Description		matrix metallopeptidase 21	clarin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix	Membrane Extracellular Exosome
	Molecular Function	Metalloendopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Proteolysis Determination Of Left/right Symmetry Extracellular Matrix Organization Collagen Catabolic Process Coronary Vasculature Development Determination Of Heart Left/right Asymmetry	Sensory Perception Of Sound
Pathways
Drugs		Marimastat
Diseases
GWAS		Metabolite levels ( 23823483)	Metabolite levels ( 23823483) Parkinson's disease (motor and cognition) ( 22658654)
Interacting Genes		4 interacting genes: CLRN3 DOCK1 FOXI2 NPS	3 interacting genes: DOCK1 MMP21 ZDHHC17
Entrez ID		118856	119467
HPRD ID		07003	14553
Ensembl ID		ENSG00000154485	ENSG00000180745
Uniprot IDs		Q8N119	Q8NCR9
PDB IDs
Enriched GO Terms of Interacting Partners?			Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Regulation Of Synapse Organization Guanyl-nucleotide Exchange Factor Complex Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity Determination Of Heart Left/right Asymmetry Glutamatergic Synapse Lipoprotein Transport Regulation Of Neurotrophin TRK Receptor Signaling Pathway Protein Palmitoylation Palmitoyltransferase Activity Regulation Of Modification Of Synaptic Structure Golgi-associated Vesicle Membrane Protein-cysteine S-palmitoyltransferase Activity Myoblast Fusion Protein Lipidation Coronary Vasculature Development Phagocytosis, Engulfment Cell-cell Fusion Syncytium Formation By Plasma Membrane Fusion Syncytium Formation Collagen Catabolic Process Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Postsynapse Assembly Membrane Invagination Positive Regulation Of Epithelial Cell Migration
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