MMP21 and NPS

		MMP21	NPS
Description		matrix metallopeptidase 21	neuropeptide S
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix	Extracellular Region Synapse
	Molecular Function	Metalloendopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Proteolysis Determination Of Left/right Symmetry Extracellular Matrix Organization Collagen Catabolic Process Coronary Vasculature Development Determination Of Heart Left/right Asymmetry	Neuropeptide Signaling Pathway Visual Learning Positive Regulation Of Circadian Sleep/wake Cycle, Wakefulness Positive Regulation Of Synaptic Transmission, GABAergic Synaptic Transmission, Glutamatergic Positive Regulation Of Action Potential Positive Regulation Of Synaptic Transmission, Glutamatergic
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events
Drugs		Marimastat
Diseases
GWAS		Metabolite levels ( 23823483)	Chronotype ( 30696823)
Interacting Genes		4 interacting genes: CLRN3 DOCK1 FOXI2 NPS	1 interacting genes: MMP21
Entrez ID		118856	594857
HPRD ID		07003	19031
Ensembl ID		ENSG00000154485	ENSG00000214285
Uniprot IDs		Q8N119	P0C0P6
PDB IDs
Enriched GO Terms of Interacting Partners?			Determination Of Heart Left/right Asymmetry Collagen Metabolic Process Collagen Catabolic Process Determination Of Bilateral Symmetry Hematopoietic Progenitor Cell Differentiation Metalloendopeptidase Activity Coronary Vasculature Development Determination Of Left/right Symmetry Metallopeptidase Activity Blood Vessel Development Extracellular Structure Organization Extracellular Matrix Organization
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