MMP21 and FOXI2

		MMP21	FOXI2
Description		matrix metallopeptidase 21	forkhead box I2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix	Chromatin Nucleus
	Molecular Function	Metalloendopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Proteolysis Determination Of Left/right Symmetry Extracellular Matrix Organization Collagen Catabolic Process Coronary Vasculature Development Determination Of Heart Left/right Asymmetry	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Cell Differentiation
Pathways
Drugs		Marimastat
Diseases
GWAS		Metabolite levels ( 23823483)	Hepcidin/transferrin saturation ratio ( 27846281)
Interacting Genes		4 interacting genes: CLRN3 DOCK1 FOXI2 NPS	1 interacting genes: MMP21
Entrez ID		118856	399823
HPRD ID		07003	13540
Ensembl ID		ENSG00000154485	ENSG00000186766
Uniprot IDs		Q8N119	Q6ZQN5
PDB IDs
Enriched GO Terms of Interacting Partners?			Determination Of Heart Left/right Asymmetry Collagen Metabolic Process Collagen Catabolic Process Determination Of Bilateral Symmetry Hematopoietic Progenitor Cell Differentiation Metalloendopeptidase Activity Coronary Vasculature Development Determination Of Left/right Symmetry Metallopeptidase Activity Blood Vessel Development Extracellular Structure Organization Extracellular Matrix Organization
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