FOXI2 and MMP21

		FOXI2	MMP21
Description		forkhead box I2	matrix metallopeptidase 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Extracellular Region Extracellular Matrix
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding	Metalloendopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Cell Differentiation	Hematopoietic Progenitor Cell Differentiation Proteolysis Determination Of Left/right Symmetry Extracellular Matrix Organization Collagen Catabolic Process Coronary Vasculature Development Determination Of Heart Left/right Asymmetry
Pathways
Drugs			Marimastat
Diseases
GWAS		Hepcidin/transferrin saturation ratio ( 27846281)	Metabolite levels ( 23823483)
Interacting Genes		1 interacting genes: MMP21	4 interacting genes: CLRN3 DOCK1 FOXI2 NPS
Entrez ID		399823	118856
HPRD ID		13540	07003
Ensembl ID		ENSG00000186766	ENSG00000154485
Uniprot IDs		Q6ZQN5	Q8N119
PDB IDs
Enriched GO Terms of Interacting Partners?		Determination Of Heart Left/right Asymmetry Collagen Metabolic Process Collagen Catabolic Process Determination Of Bilateral Symmetry Hematopoietic Progenitor Cell Differentiation Metalloendopeptidase Activity Coronary Vasculature Development Determination Of Left/right Symmetry Metallopeptidase Activity Blood Vessel Development Extracellular Structure Organization Extracellular Matrix Organization
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