KIR3DL1 and KIR2DS1

		KIR3DL1	KIR2DS1
Description		killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Amyloid-beta Binding Protein Binding HLA-B Specific Inhibitory MHC Class I Receptor Activity Molecular Adaptor Activity	Transmembrane Signaling Receptor Activity Protein Binding
	Biological Process	Immune Response-regulating Signaling Pathway Immune Response Natural Killer Cell Mediated Cytotoxicity	Immune Response-regulating Signaling Pathway Immune Response
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		11 interacting genes: BMP10 CDK3 FPR1 HLA-B KIR2DS1 KIR2DS5 KIR3DS1 RPS6KB1 SMCO4 TAFA2 THSD7B	2 interacting genes: HLA-C KIR3DL1
Entrez ID		3811	3806
HPRD ID		09226	05384
Ensembl ID		ENSG00000167633
Uniprot IDs		P43629 Q5UCE2 Q6H2G3 Q8N6C9	A0A7D4Y6C7 B1N8M6 Q14954
PDB IDs		3VH8 3WUW 5B38 5B39 5T6Z 5T70 6V3J 7K80 7K81 9BL2 9BL3 9BL4 9BL5 9BL6 9BL9 9BLA
Enriched GO Terms of Interacting Partners?		Regulation Of Immune Response Immune Response-regulating Signaling Pathway	TAP Binding HLA-B Specific Inhibitory MHC Class I Receptor Activity Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response MHC Class I Protein Complex Lumenal Side Of Endoplasmic Reticulum Membrane Innate Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Response To Other Organism Positive Regulation Of Natural Killer Cell Mediated Immunity Defense Response To Other Organism Antigen Processing And Presentation Of Endogenous Antigen Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Binding Defense Response To Symbiont Immune Response Defense Response Regulation Of T Cell Mediated Cytotoxicity Response To External Biotic Stimulus Regulation Of Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity ER To Golgi Transport Vesicle Membrane Regulation Of Natural Killer Cell Mediated Immunity Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of T Cell Mediated Immunity Regulation Of Immune System Process Positive Regulation Of Cell Killing Leukocyte Mediated Cytotoxicity Phagocytic Vesicle Membrane Amyloid-beta Binding Antigen Processing And Presentation Immune System Process Secretory Granule Membrane Regulation Of Leukocyte Mediated Cytotoxicity Recycling Endosome Membrane Regulation Of T Cell Mediated Immunity Lymphocyte Mediated Immunity Receptor Ligand Activity Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Leukocyte Mediated Immunity Molecular Adaptor Activity Cell Killing Regulation Of Lymphocyte Mediated Immunity
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