KIR3DL1 and TAFA2

Number of citations of the paper that reports this interaction (PubMedID 36178190)
90

Data Source:
BioGRID (pull down)

		KIR3DL1	TAFA2
Description		killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	TAFA chemokine like family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Extracellular Space Nucleus Cytoplasm
	Molecular Function	Amyloid-beta Binding Protein Binding HLA-B Specific Inhibitory MHC Class I Receptor Activity Molecular Adaptor Activity	Receptor Ligand Activity
	Biological Process	Immune Response-regulating Signaling Pathway Immune Response Natural Killer Cell Mediated Cytotoxicity	Signal Transduction Memory Visual Learning
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494) Ulcerative colitis ( 28067908)	Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485)
Interacting Genes		7 interacting genes: BMP10 CDK3 HLA-B RPS6KB1 SMCO4 TAFA2 THSD7B	5 interacting genes: KIR2DL5A KIR3DL1 KIR3DL2 KIR3DL3 RNF167
Entrez ID		3811	338811
HPRD ID		09226	16876
Ensembl ID		ENSG00000167633	ENSG00000198673
Uniprot IDs		P43629 Q5UCE2 Q6H2G3 Q8N6C9	Q8N3H0
PDB IDs		3VH8 3WUW 5B38 5B39 5T6Z 5T70 6V3J 7K80 7K81 9BL2 9BL3 9BL4 9BL5 9BL6 9BL9 9BLA
Enriched GO Terms of Interacting Partners?		Regulation Of Immune Response Immune Response-regulating Signaling Pathway	Immune Response-regulating Signaling Pathway Regulation Of Immune Response Regulation Of Immune System Process HLA-B Specific Inhibitory MHC Class I Receptor Activity Plasma Membrane MHC Class Ib Protein Binding Cellular Response To Leucine Starvation Protein K29-linked Ubiquitination
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