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KIR2DS1
Description
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
Protein Binding
Biological Process
Immune Response-regulating Signaling Pathway
Immune Response
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
DAP12 interactions
Drugs
Diseases
GWAS
Novel Interacting Genes
2 novel interacting genes:
HLA-C
KIR3DL1
Interacting Genes
2 interacting genes:
HLA-C
KIR3DL1
Entrez ID
3806
HPRD ID
05384
Ensembl ID
Uniprot IDs
A0A7D4Y6C7
B1N8M6
Q14954
PDB IDs
Enriched GO Terms of Interacting Partners
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TAP Binding
HLA-B Specific Inhibitory MHC Class I Receptor Activity
Positive Regulation Of T Cell Mediated Cytotoxicity
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Immune Response
MHC Class I Protein Complex
Lumenal Side Of Endoplasmic Reticulum Membrane
Innate Immune Response
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent
Response To Other Organism
Positive Regulation Of Natural Killer Cell Mediated Immunity
Defense Response To Other Organism
Antigen Processing And Presentation Of Endogenous Antigen
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I
Peptide Antigen Binding
Defense Response To Symbiont
Immune Response
Defense Response
Regulation Of T Cell Mediated Cytotoxicity
Response To External Biotic Stimulus
Regulation Of Natural Killer Cell Mediated Cytotoxicity
Natural Killer Cell Mediated Immunity
Natural Killer Cell Mediated Cytotoxicity
ER To Golgi Transport Vesicle Membrane
Regulation Of Natural Killer Cell Mediated Immunity
Antigen Processing And Presentation Of Peptide Antigen
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Positive Regulation Of T Cell Mediated Immunity
Regulation Of Immune System Process
Positive Regulation Of Cell Killing
Leukocyte Mediated Cytotoxicity
Phagocytic Vesicle Membrane
Amyloid-beta Binding
Antigen Processing And Presentation
Immune System Process
Secretory Granule Membrane
Regulation Of Leukocyte Mediated Cytotoxicity
Recycling Endosome Membrane
Regulation Of T Cell Mediated Immunity
Lymphocyte Mediated Immunity
Receptor Ligand Activity
Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Positive Regulation Of Lymphocyte Mediated Immunity
Positive Regulation Of Adaptive Immune Response
Leukocyte Mediated Immunity
Molecular Adaptor Activity
Cell Killing
Regulation Of Lymphocyte Mediated Immunity
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