GGT3P and PRODH

		GGT3P	PRODH
Description		gamma-glutamyltransferase 3 pseudogene	proline dehydrogenase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Peptidase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity Glutathione Hydrolase Activity Leukotriene C4 Gamma-glutamyl Transferase Activity	Proline Dehydrogenase Activity Oxidoreductase Activity FAD Binding
	Biological Process	Regulation Of Immune System Process Proteolysis Glutathione Metabolic Process Glutathione Biosynthetic Process Glutathione Catabolic Process Peptide Modification Regulation Of Inflammatory Response Leukotriene D4 Biosynthetic Process	Proline Metabolic Process L-proline Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress L-proline Catabolic Process To L-glutamate Trans-4-hydroxy-L-proline Catabolic Process Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways			Proline catabolism
Drugs			Proline
Diseases			Hyperprolinemia (HP)
GWAS			Metabolic traits ( 21886157) Metabolite levels ( 31628463) Neutrophil count ( 32888494) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free proline levels ( 30659259) Platelet count ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 25569235 33031748) White blood cell count ( 32888494)
Interacting Genes		1 interacting genes: PRODH	7 interacting genes: GGT3P GSC2 ITM2C RANBP1 SEPTIN5 SKIC2 TBX1
Entrez ID		2679	5625
HPRD ID		08843	08433
Ensembl ID		ENSG00000197421	ENSG00000100033
Uniprot IDs			E7EQL6 O43272
PDB IDs
Enriched GO Terms of Interacting Partners?		L-proline Catabolic Process To L-glutamate Trans-4-hydroxy-L-proline Catabolic Process L-proline Catabolic Process Proline Dehydrogenase Activity Proline Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Glutamate Metabolic Process Modified Amino Acid Catabolic Process FAD Binding Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Glutamine Family Amino Acid Metabolic Process Proteinogenic Amino Acid Catabolic Process L-amino Acid Catabolic Process Dicarboxylic Acid Metabolic Process Amino Acid Catabolic Process Modified Amino Acid Metabolic Process L-amino Acid Metabolic Process Intrinsic Apoptotic Signaling Pathway Alpha-amino Acid Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Carboxylic Acid Catabolic Process Regulation Of Neuron Apoptotic Process Amino Acid Metabolic Process Apoptotic Signaling Pathway Regulation Of Apoptotic Signaling Pathway Mitochondrial Matrix Mitochondrial Inner Membrane	Social Behavior
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