PRODH

Description		proline dehydrogenase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Proline Dehydrogenase Activity Oxidoreductase Activity FAD Binding
	Biological Process	Proline Metabolic Process L-proline Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress L-proline Catabolic Process To L-glutamate Trans-4-hydroxy-L-proline Catabolic Process Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways		Proline catabolism
Drugs		Proline
Diseases		Hyperprolinemia (HP)
GWAS		Metabolic traits ( 21886157) Metabolite levels ( 31628463) Neutrophil count ( 32888494) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free proline levels ( 30659259) Platelet count ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 25569235 33031748) White blood cell count ( 32888494)
Novel Interacting Genes		7 novel interacting genes: GGT3P GSC2 ITM2C RANBP1 SEPTIN5 SKIC2 TBX1
Interacting Genes
Entrez ID		5625
HPRD ID		08433
Ensembl ID		ENSG00000100033
Uniprot IDs		E7EQL6 O43272
PDB IDs
Enriched GO Terms of Interacting Partners?		Social Behavior
Tagcloud ?