SYNE4 and TMEM248

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SYNE4	TMEM248
Description		spectrin repeat containing nuclear envelope family member 4	transmembrane protein 248
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Outer Membrane Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways
Drugs
Diseases
GWAS
Interacting Genes		57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CFTR CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648	27 interacting genes: ANKRD46 ARL6IP1 ARLN BARD1 BRICD5 CLDN19 FAM3C GPR25 GPR37L1 GRM2 LEPROTL1 LHFPL5 MAL MALL RUSF1 RXFP3 SLC35B2 SLC41A1 SYNE4 SYS1 TMEM147 TMEM239 TMEM86B TRARG1 VSTM1 YIF1A YIPF1
Entrez ID		163183	55069
HPRD ID		08776	08541
Ensembl ID		ENSG00000181392	ENSG00000106609
Uniprot IDs		Q8N205	Q9NWD8
PDB IDs		6R16 6WMD
Enriched GO Terms of Interacting Partners?		Protein Binding Bicellular Tight Junction Assembly Tight Junction Organization Tight Junction Assembly Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Apicolateral Plasma Membrane Regulation Of Glycogen (starch) Synthase Activity	Membrane Establishment Of Protein Localization To Membrane Schmidt-Lanterman Incisure Structural Constituent Of Myelin Sheath
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