SYNE4 and WDR62

		SYNE4	WDR62
Description		spectrin repeat containing nuclear envelope family member 4	WD repeat domain 62
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Outer Membrane Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Spindle Pole Nucleus Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Centriolar Satellite
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Positive Regulation Of Neuroblast Proliferation Mitotic Spindle Organization Centriole Replication Nervous System Development Cerebral Cortex Development Neurogenesis Regulation Of Neuron Differentiation Regulation Of Centrosome Cycle Positive Regulation Of Neuron Migration
Pathways
Drugs
Diseases
GWAS
Interacting Genes		57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CFTR CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648	18 interacting genes: DYRK2 ENKD1 LRIF1 MAGEB4 MAPK8 MAPK9 P4HA3 RALY SYNE4 TBC1D23 TBP THAP8 U2AF1L4 ZFP82 ZNF260 ZNF540 ZNF585A ZNF875
Entrez ID		163183	284403
HPRD ID		08776	10721
Ensembl ID		ENSG00000181392	ENSG00000075702
Uniprot IDs		Q8N205	A0A7P0T9D9 A0A7P0TAK3 A0A7P0Z436 O43379
PDB IDs		6R16 6WMD
Enriched GO Terms of Interacting Partners?		Protein Binding Bicellular Tight Junction Assembly Tight Junction Organization Tight Junction Assembly Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Apicolateral Plasma Membrane Regulation Of Glycogen (starch) Synthase Activity	JUN Kinase Activity Regulation Of RNA Metabolic Process MAP Kinase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Fc-epsilon Receptor Signaling Pathway Protein Serine/threonine/tyrosine Kinase Activity Nucleus Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process JUN Phosphorylation
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