CLRN3 and MMP21

		CLRN3	MMP21
Description		clarin 3	matrix metallopeptidase 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Extracellular Exosome	Extracellular Region Extracellular Matrix
	Molecular Function	Protein Binding	Metalloendopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Sensory Perception Of Sound	Hematopoietic Progenitor Cell Differentiation Proteolysis Determination Of Left/right Symmetry Extracellular Matrix Organization Collagen Catabolic Process Coronary Vasculature Development Determination Of Heart Left/right Asymmetry
Pathways
Drugs			Marimastat
Diseases
GWAS		Metabolite levels ( 23823483) Parkinson's disease (motor and cognition) ( 22658654)	Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: DOCK1 MMP21 ZDHHC17	4 interacting genes: CLRN3 DOCK1 FOXI2 NPS
Entrez ID		119467	118856
HPRD ID		14553	07003
Ensembl ID		ENSG00000180745	ENSG00000154485
Uniprot IDs		Q8NCR9	Q8N119
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Regulation Of Synapse Organization Guanyl-nucleotide Exchange Factor Complex Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity Determination Of Heart Left/right Asymmetry Glutamatergic Synapse Lipoprotein Transport Regulation Of Neurotrophin TRK Receptor Signaling Pathway Protein Palmitoylation Palmitoyltransferase Activity Regulation Of Modification Of Synaptic Structure Golgi-associated Vesicle Membrane Protein-cysteine S-palmitoyltransferase Activity Myoblast Fusion Protein Lipidation Coronary Vasculature Development Phagocytosis, Engulfment Cell-cell Fusion Syncytium Formation By Plasma Membrane Fusion Syncytium Formation Collagen Catabolic Process Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Postsynapse Assembly Membrane Invagination Positive Regulation Of Epithelial Cell Migration
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