FRA10AC1 and THOC1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		FRA10AC1	THOC1
Description		FRA10A associated CGG repeat 1	THO complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Protein Binding Phosphatase Activity	DNA Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	MRNA Processing MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing MRNA Transport
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321) Refractive error ( 32231278)	Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799) Triglyceride levels ( 32203549)
Interacting Genes		27 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D GATD3 GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 MOB2 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830	34 interacting genes: AGR2 AKAP9 ATP1B1 CTAG1A CTAG1B DHX8 ESS2 EXOC5 EXOSC7 FRA10AC1 GPRASP3 IK MAGEB4 MOAP1 MTNR1B NEDD4 PAX6 PPP1R12C PRC1 PRPF6 RABGEF1 RB1 REL SAP30BP SF3B2 SNW1 TADA2A TFIP11 TRIM27 TRIM54 TYMS USHBP1 WDR77 ZMYND12
Entrez ID		118924	9984
HPRD ID		12319	09498
Ensembl ID		ENSG00000148690	ENSG00000079134
Uniprot IDs		Q70Z53	Q96FV9
PDB IDs			1WXP 7APK 7ZNK 7ZNL
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing U2-type Precatalytic Spliceosome MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Nuclear Speck Spliceosomal Complex Nucleic Acid Metabolic Process RNA Metabolic Process Nucleoplasm RNA Binding Cajal Body Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome U2-type Spliceosomal Complex Glycerophosphoinositol Inositolphosphodiesterase Activity ADP-ribosylserine Hydrolase Activity Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation Nucleus Nucleic Acid Binding	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Catalytic Step 2 Spliceosome Spliceosomal Complex RNA Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Processing Cyclin/CDK Positive Transcription Elongation Factor Complex U2-type Precatalytic Spliceosome
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