FRA10AC1 and GDPD2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FRA10AC1	GDPD2
Description		FRA10A associated CGG repeat 1	glycerophosphodiester phosphodiesterase domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane Membrane Lamellipodium
	Molecular Function	Protein Binding Phosphatase Activity	Phosphoric Diester Hydrolase Activity Glycerophosphodiester Phosphodiesterase Activity Hydrolase Activity Metal Ion Binding Glycerophosphoinositol Inositolphosphodiesterase Activity
	Biological Process	MRNA Splicing, Via Spliceosome	Lipid Metabolic Process Actin Filament Organization Positive Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321) Refractive error ( 32231278)
Interacting Genes		27 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D GATD3 GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 MOB2 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830	6 interacting genes: ATP5F1C DRD2 FRA10AC1 HEXD PDZD11 SGSM2
Entrez ID		118924	54857
HPRD ID		12319	06528
Ensembl ID		ENSG00000148690	ENSG00000130055
Uniprot IDs		Q70Z53	Q9HCC8
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing U2-type Precatalytic Spliceosome MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Nuclear Speck Spliceosomal Complex Nucleic Acid Metabolic Process RNA Metabolic Process Nucleoplasm RNA Binding Cajal Body Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome U2-type Spliceosomal Complex Glycerophosphoinositol Inositolphosphodiesterase Activity ADP-ribosylserine Hydrolase Activity Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation Nucleus Nucleic Acid Binding	Proton-transporting ATP Synthase Activity, Rotational Mechanism Negative Regulation Of Synaptic Transmission, Glutamatergic Auditory Behavior Cellular Response To Ethanol Response To Histamine Regulation Of Synapse Structural Plasticity Anatomical Structure Regression Dopamine Binding Regulation Of Renal Sodium Excretion Dopamine Neurotransmitter Receptor Activity Regulation Of Synapse Organization Cerebral Cortex GABAergic Interneuron Migration Negative Regulation Of Cellular Response To Hypoxia Regulation Of Developmental Growth Neurotransmitter Transport Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway G Protein-coupled Receptor Complex Catecholamine Uptake Dopamine Uptake Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Adenohypophysis Development Negative Regulation Of Dephosphorylation Response To Inactivity Positive Regulation Of Renal Sodium Excretion Interneuron Migration Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Negative Regulation Of Neuron Migration Negative Regulation Of Circadian Rhythm Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Grooming Behavior Hyaloid Vascular Plexus Regression Regulation Of Growth Hormone Secretion Dopaminergic Synapse Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Prepulse Inhibition Neuron-neuron Synaptic Transmission Interneuron Migration From The Subpallium To The Cortex Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Peristalsis Striatum Development Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Uptake Involved In Synaptic Transmission G Protein-coupled Receptor Internalization Heterotrimeric G-protein Binding
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