PRRT2 and TLCD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRRT2	TLCD4
Description		proline rich transmembrane protein 2	TLC domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Membrane Axon Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Presynaptic Membrane Cell Projection Dendritic Spine Axon Terminus Synapse Postsynaptic Membrane Presynapse Postsynaptic Density Membrane Glutamatergic Synapse	Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Syntaxin-1 Binding	Protein Binding
	Biological Process	Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of SNARE Complex Assembly Neuromuscular Process Controlling Posture Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Negative Regulation Of Short-term Synaptic Potentiation	Lipid Homeostasis
Pathways
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: AQP6 CFAP119 F2RL1 GPRC5D KAT8 ORAI3 SLC10A6 SLC71A2 SMIM5 SNAP25 TLCD4 TMEM219 ZNF689	73 interacting genes: ADGRB3 ADGRE2 ARV1 ATP13A1 BNIP3 CACNG1 CCDC167 CDIPT CFTR CHPT1 CLCN7 CLEC7A CMTM5 COMT CTXN3 CXCL16 CYP4F2 CYP4F22 DHRSX EBP EMC6 EMP1 ERG28 FA2H FDFT1 FXYD6 FXYD6-FXYD2 GJB2 GOSR2 GYPA HMOX1 IGFBP5 KRT1 LNPEP MIR137HG MS4A13 MYG1 NAT8 NDUFA3 NINJ1 NKG7 ORMDL1 PMP22 PRAF2 PRRT2 REEP6 SCAMP5 SCD SEC22A SEC22B SERP1 SFXN1 SFXN3 SLC41A1 SLC67A1 SMAGP STATH STX12 SYNDIG1 SYNJ2BP TIMM23 TMEM115 TMEM120B TMEM19 TMEM229B TMEM237 TMEM60 TMIE TVP23B UBE2J1 VEZT YIPF1 YIPF4
Entrez ID		112476	148534
HPRD ID		13995	08110
Ensembl ID		ENSG00000167371	ENSG00000152078
Uniprot IDs		Q7Z6L0	Q96MV1
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Sterol Biosynthetic Process Lipid Biosynthetic Process Cholesterol Biosynthetic Process SNAP Receptor Activity Steroid Biosynthetic Process Membrane Fusion Serine Import Into Mitochondrion Lipid Metabolic Process Sterol Metabolic Process Cholesterol Transport Establishment Of Protein Localization Sterol Transport Membrane Organization Organic Cation Transport Import Into The Mitochondrion Protein Transport L-serine Transmembrane Transporter Activity L-serine Transport Protein Binding Bleb Assembly Serine Transport Vesicle Fusion
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