PRRT2 and ORAI3

		PRRT2	ORAI3
Description		proline rich transmembrane protein 2	ORAI calcium release-activated calcium modulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Membrane Axon Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Presynaptic Membrane Cell Projection Dendritic Spine Axon Terminus Synapse Postsynaptic Membrane Presynapse Postsynaptic Density Membrane Glutamatergic Synapse	Plasma Membrane Membrane
	Molecular Function	Protein Binding Syntaxin-1 Binding	Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity
	Biological Process	Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of SNARE Complex Assembly Neuromuscular Process Controlling Posture Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Negative Regulation Of Short-term Synaptic Potentiation	Store-operated Calcium Entry Monoatomic Ion Transport Calcium Ion Transport Monoatomic Ion Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS			Basophil percentage of white cells ( 32888494) Hematocrit ( 32888494)
Interacting Genes		13 interacting genes: AQP6 CFAP119 F2RL1 GPRC5D KAT8 ORAI3 SLC10A6 SLC71A2 SMIM5 SNAP25 TLCD4 TMEM219 ZNF689	2 interacting genes: KAT8 PRRT2
Entrez ID		112476	93129
HPRD ID		13995	14431
Ensembl ID		ENSG00000167371	ENSG00000175938
Uniprot IDs		Q7Z6L0	Q9BRQ5
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Skeletal Muscle Satellite Cell Differentiation Protein Propionyltransferase Activity Negative Regulation Of Short-term Synaptic Potentiation Negative Regulation Of SNARE Complex Assembly Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion MSL Complex Negative Regulation Of Vesicle Fusion Post-embryonic Hemopoiesis NSL Complex Skeletal Muscle Satellite Cell Differentiation Histone H4K8 Acetyltransferase Activity Histone H4K16 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Positive Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Mitochondrial Transcription Vesicle Fusion To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Histone H4 Acetyltransferase Activity Neuromuscular Process Controlling Posture Synaptic Vesicle Membrane Organization Regulation Of SNARE Complex Assembly Syntaxin-1 Binding Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Acetyltransferase Activity Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Regulation Of Skeletal Muscle Cell Differentiation Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity NuA4 Histone Acetyltransferase Complex MLL1 Complex Histone Acetyltransferase Activity Regulation Of Vesicle Fusion Nuclear Lumen Oogenesis Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Type I Interferon Production Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Axon Terminus Skeletal Muscle Cell Differentiation Positive Regulation Of Epithelial To Mesenchymal Transition Female Gamete Generation Positive Regulation Of Transcription Initiation By RNA Polymerase II Promoter-specific Chromatin Binding Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Epithelial To Mesenchymal Transition Positive Regulation Of Type I Interferon Production
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