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TLCD4 and SYNJ2BP
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
TLCD4
SYNJ2BP
Description
TLC domain containing 4
synaptojanin 2 binding protein
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Membrane
Mitochondrion
Mitochondrial Outer Membrane
Membrane
Molecular Function
Protein Binding
Protein Binding
Biological Process
Lipid Homeostasis
Negative Regulation Of Endothelial Cell Proliferation
Protein Targeting
Rho Protein Signal Transduction
Regulation Of Notch Signaling Pathway
Negative Regulation Of Endothelial Cell Migration
Negative Regulation Of Angiogenesis
Regulation Of Endocytosis
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS
Blood pressure (
24954895
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
LDL cholesterol (
30275531
)
Motor coordination (
34177493
)
Normal facial asymmetry (angle of surface orientation score) (
30631343
)
Interacting Genes
73 interacting genes:
ADGRB3
ADGRE2
ARV1
ATP13A1
BNIP3
CACNG1
CCDC167
CDIPT
CFTR
CHPT1
CLCN7
CLEC7A
CMTM5
COMT
CTXN3
CXCL16
CYP4F2
CYP4F22
DHRSX
EBP
EMC6
EMP1
ERG28
FA2H
FDFT1
FXYD6
FXYD6-FXYD2
GJB2
GOSR2
GYPA
HMOX1
IGFBP5
KRT1
LNPEP
MIR137HG
MS4A13
MYG1
NAT8
NDUFA3
NINJ1
NKG7
ORMDL1
PMP22
PRAF2
PRRT2
REEP6
SCAMP5
SCD
SEC22A
SEC22B
SERP1
SFXN1
SFXN3
SLC41A1
SLC67A1
SMAGP
STATH
STX12
SYNDIG1
SYNJ2BP
TIMM23
TMEM115
TMEM120B
TMEM19
TMEM229B
TMEM237
TMEM60
TMIE
TVP23B
UBE2J1
VEZT
YIPF1
YIPF4
35 interacting genes:
ACTB
ACVR2A
ACVR2B
APP
AQP6
CD79A
CPLX4
CREB3L1
CYB561
EBP
ELOVL5
ELOVL7
ERGIC3
FAM210B
FCER1G
LHFPL5
LRP1
LRP2
LRP8
MEDAG
RALBP1
REEP4
RPS6KA1
SLC10A6
SLC7A8
SMOC1
SYNJ2
THEM5
TLCD4
TMEM101
TMEM14B
TMEM242
UBQLN1
USHBP1
VANGL2
Entrez ID
148534
55333
HPRD ID
08110
15455
Ensembl ID
ENSG00000152078
ENSG00000213463
Uniprot IDs
Q96MV1
P57105
PDB IDs
2ENO
2JIK
2JIN
7P73
7P74
7PC9
7R2M
7R2T
8AEL
Enriched GO Terms of Interacting Partners
?
Membrane
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum
Sterol Biosynthetic Process
Lipid Biosynthetic Process
Cholesterol Biosynthetic Process
SNAP Receptor Activity
Steroid Biosynthetic Process
Membrane Fusion
Serine Import Into Mitochondrion
Lipid Metabolic Process
Sterol Metabolic Process
Cholesterol Transport
Establishment Of Protein Localization
Sterol Transport
Membrane Organization
Organic Cation Transport
Import Into The Mitochondrion
Protein Transport
L-serine Transmembrane Transporter Activity
L-serine Transport
Protein Binding
Bleb Assembly
Serine Transport
Vesicle Fusion
Membrane
Receptor Complex
Low-density Lipoprotein Particle Receptor Activity
Apolipoprotein Binding
Activin Receptor Activity, Type II
Activin Receptor Activity
Endocytosis
Import Into Cell
Astrocyte Activation Involved In Immune Response
Cargo Receptor Activity
Long-chain Fatty-acyl-CoA Metabolic Process
Positive Regulation Of Lysosomal Protein Catabolic Process
Positive Regulation Of Cell Differentiation
Positive Regulation Of Activin Receptor Signaling Pathway
Activin Receptor Complex
Positive Regulation Of Protein Catabolic Process In The Vacuole
Fatty Acid Elongase Activity
Fatty Acid Elongation, Polyunsaturated Fatty Acid
Fatty Acid Elongation, Monounsaturated Fatty Acid
Fatty Acid Elongation, Saturated Fatty Acid
Protein Binding
Activin Binding
Regulation Of Lysosomal Protein Catabolic Process
Positive Regulation Of Developmental Process
Cellular Response To Growth Factor Stimulus
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Very Long-chain Fatty Acid Biosynthetic Process
Fatty Acid Elongation
Apical Protein Localization
Response To Growth Factor
Clathrin-coated Pit
Vesicle-mediated Transport
Plasma Membrane Protein Complex
Receptor-mediated Endocytosis
Retinoid Metabolic Process
Regulation Of Developmental Process
Gastrulation With Mouth Forming Second
Heparan Sulfate Proteoglycan Binding
Astrocyte Activation
Transport Across Blood-brain Barrier
Diterpenoid Metabolic Process
Fatty Acid Derivative Metabolic Process
Endoplasmic Reticulum
Transcytosis
Long-chain Fatty-acyl-CoA Biosynthetic Process
Regulation Of Amyloid-beta Clearance
Regulation Of Cell Differentiation
Acyl-CoA Metabolic Process
Positive Regulation Of Protein Catabolic Process
Regulation Of Response To Endoplasmic Reticulum Stress
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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