EMG1 and PSME1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		EMG1	PSME1
Description		EMG1 N1-specific pseudouridine methyltransferase	proteasome activator subunit 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Small-subunit Processome	Proteasome Complex Nucleoplasm Cytoplasm Cytosol Proteasome Activator Complex Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity Transferase Activity RRNA Binding Identical Protein Binding RRNA (pseudouridine) Methyltransferase Activity	Protein Binding Endopeptidase Activator Activity
	Biological Process	Blastocyst Development RRNA Processing Nucleologenesis Methylation Ribosome Biogenesis Ribosomal Small Subunit Biogenesis RRNA Base Methylation	Antigen Processing And Presentation Of Exogenous Antigen Regulation Of Proteasomal Protein Catabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	ER-Phagosome pathway Cross-presentation of soluble exogenous antigens (endosomes) Proteasome assembly Proteasome assembly Antigen processing: Ub, ATP-independent proteasomal degradation
Drugs			Copper
Diseases		Bowen-Conradi syndrome (BCS)
GWAS
Interacting Genes		20 interacting genes: ANXA3 APP CEBPA CFTR CTSE FAM74A4 FAM98A HIVEP1 HSD3B7 IL7R KHDRBS1 MCPH1 NAA80 PRC1 PSMB7 PSME1 SLC25A38 SUMO2 ZCCHC9 ZNF768	23 interacting genes: AIMP2 APP ATP1B1 CDC37 CEBPA CHD3 EIF6 EMD EMG1 FXR1 FXR2 PFDN1 PIK3R3 PSME2 RPP14 SETDB1 SMN1 TK1 TTC3 TUBB4B USP22 VCL VIM
Entrez ID		10436	5720
HPRD ID		12803	02803
Ensembl ID		ENSG00000126749	ENSG00000092010
Uniprot IDs		Q92979	A0A0K0K1L8 Q06323 Q86SZ9
PDB IDs		5FAI 7MQ8 7MQ9 7MQA	1AVO 7DR6 7DRW 7NAO 7NAP 8CXB
Enriched GO Terms of Interacting Partners?			Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Neuron Projection Protein Heterodimerization Activity Regulation Of Protein Metabolic Process Negative Regulation Of Long-term Synaptic Potentiation Post-transcriptional Regulation Of Gene Expression Cytoplasm Positive Regulation Of Gene Expression Costamere Cytoplasmic Ribonucleoprotein Granule Nucleolus Extracellular Vesicle Regulation Of Amyloid Fibril Formation Translation Regulator Activity Cytosol Unfolded Protein Binding Dentate Gyrus Development Positive Regulation Of Protein Metabolic Process Amyloid Fibril Formation Nucleus Positive Regulation Of Catabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding TMEM240-body Assembly Of Large Subunit Precursor Of Preribosome Positive Regulation Of Translation Inner Dense Plaque Of Desmosome Podosome Ring Outer Dense Plaque Of Desmosome RRNA (pseudouridine) Methyltransferase Activity Presynaptic Modulation Of Chemical Synaptic Transmission
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