EMG1 and ANXA3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		EMG1	ANXA3
Description		EMG1 N1-specific pseudouridine methyltransferase	annexin A3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Small-subunit Processome	Nucleus Cytoplasm Plasma Membrane Vesicle Membrane Membrane Phagocytic Vesicle Membrane Specific Granule Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity Transferase Activity RRNA Binding Identical Protein Binding RRNA (pseudouridine) Methyltransferase Activity	Phosphatidylserine Binding Phospholipase Inhibitor Activity Calcium Ion Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Calcium-dependent Protein Binding
	Biological Process	Blastocyst Development RRNA Processing Nucleologenesis Methylation Ribosome Biogenesis Ribosomal Small Subunit Biogenesis RRNA Base Methylation	Phagocytosis Positive Regulation Of Endothelial Cell Migration Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Angiogenesis Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Developmental Lineage of Pancreatic Ductal Cells
Drugs			Fluocinolone acetonide Ethanolamine Difluocortolone
Diseases		Bowen-Conradi syndrome (BCS)
GWAS			Amyotrophic lateral sclerosis (sporadic) ( 24529757) Daytime nap ( 33568662) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Metabolite levels ( 23823483) Non-albumin protein levels ( 22558069) Refractive error ( 32231278) Rheumatoid arthritis ( 22446963 30423114)
Interacting Genes		20 interacting genes: ANXA3 APP CEBPA CFTR CTSE FAM74A4 FAM98A HIVEP1 HSD3B7 IL7R KHDRBS1 MCPH1 NAA80 PRC1 PSMB7 PSME1 SLC25A38 SUMO2 ZCCHC9 ZNF768	7 interacting genes: BAG5 EMG1 IGSF21 REG3A TP53 UBR1 UNC119
Entrez ID		10436	306
HPRD ID		12803	00111
Ensembl ID		ENSG00000126749	ENSG00000138772
Uniprot IDs		Q92979	P12429
PDB IDs		5FAI 7MQ8 7MQ9 7MQA	1AII 1AXN
Enriched GO Terms of Interacting Partners?			Response To Symbiotic Bacterium Response To Symbiont Positive Regulation Of Detection Of Glucose Protein-folding Chaperone Binding Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Histone Deacetylase Regulator Activity Negative Regulation Of Pentose-phosphate Shunt Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Response To Actinomycin D T Cell Proliferation Involved In Immune Response Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of Proteolysis Glial Cell Apoptotic Process Cellular Response To UV-C Germ Cell Nucleus Cellular Response To Actinomycin D ATP-dependent DNA/DNA Annealing Activity Negative Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Protein Refolding Negative Regulation Of Protein Folding RRNA (pseudouridine) Methyltransferase Activity Nucleologenesis Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway Negative Regulation Of Cellular Component Organization B Cell Lineage Commitment Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Pentose-phosphate Shunt Junctional Membrane Complex Nucleolus Organization Mitochondrial DNA Repair Bone Marrow Development Stress-induced Premature Senescence Regulation Of Caveolin-mediated Endocytosis L-leucine Binding
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