TLK1 and LUZP4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TLK1	LUZP4
Description		tousled like kinase 1	leucine zipper protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	RNA Binding Protein Binding
	Biological Process	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Intracellular Protein Transport Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Peptidyl-serine Phosphorylation Intracellular Signal Transduction	MRNA Transport
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Fostamatinib
Diseases
GWAS		Health literacy ( 31250787) Liver enzyme levels (alkaline phosphatase) ( 33972514) Menopause (age at onset) ( 22267201 26414677) Platelet distribution width ( 32888494 27863252)
Interacting Genes		29 interacting genes: ASF1A ASF1B AURKA BEND7 BHLHB9 CHEK1 CXCR5 DPPA4 DYNLL2 H1-1 LHX2 LUZP4 MBP NBN PAX6 PINX1 PTPN11 RAD9A SNAP23 TFCP2 TLK2 TPM3 UBE3C YAF2 YWHAE ZNF655 ZNF773 ZNF829 ZSCAN22	22 interacting genes: APPBP2 BACH2 CCDC6 CLK2 DDX39B DVL3 EMD FOS FOSL2 HSF2BP KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 LNX1 MORF4L2 NXF1 RCOR3 SRPK2 SRRM4 TLK1 TNS2
Entrez ID		9874	51213
HPRD ID		12232	06589
Ensembl ID		ENSG00000198586	ENSG00000102021
Uniprot IDs		Q9UKI8	Q9P127
PDB IDs
Enriched GO Terms of Interacting Partners?
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