TLK1 and ZSCAN22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TLK1	ZSCAN22
Description		tousled like kinase 1	zinc finger and SCAN domain containing 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Molecular_function Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Intracellular Protein Transport Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Peptidyl-serine Phosphorylation Intracellular Signal Transduction	Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Health literacy ( 31250787) Liver enzyme levels (alkaline phosphatase) ( 33972514) Menopause (age at onset) ( 22267201 26414677) Platelet distribution width ( 32888494 27863252)
Interacting Genes		29 interacting genes: ASF1A ASF1B AURKA BEND7 BHLHB9 CHEK1 CXCR5 DPPA4 DYNLL2 H1-1 LHX2 LUZP4 MBP NBN PAX6 PINX1 PTPN11 RAD9A SNAP23 TFCP2 TLK2 TPM3 UBE3C YAF2 YWHAE ZNF655 ZNF773 ZNF829 ZSCAN22	30 interacting genes: BYSL CDR2L DVL3 KCTD19 NEXN PGBD1 PRPF31 SCAND1 SERTAD2 TLK1 ZGPAT ZKSCAN4 ZKSCAN7 ZNF174 ZNF24 ZNF263 ZNF397 ZNF444 ZNF446 ZNF449 ZNF483 ZNF496 ZSCAN1 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN23 ZSCAN25 ZSCAN32 ZSCAN9
Entrez ID		9874	342945
HPRD ID		12232	01315
Ensembl ID		ENSG00000198586	ENSG00000182318
Uniprot IDs		Q9UKI8	P10073
PDB IDs
Enriched GO Terms of Interacting Partners?
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