DCAF1 and PWP1

Number of citations of the paper that reports this interaction (PubMedID 33355139)
1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study)

		DCAF1	PWP1
Description		DDB1 and CUL4 associated factor 1	PWP1 homolog, endonuclein
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Chromosome Nucleolus Golgi Apparatus
	Molecular Function	Protein Binding ATP Binding Estrogen Receptor Binding Protein Serine Kinase Activity Histone Kinase Activity (H2A-T120 Specific)	H4K20me3 Modified Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination B Cell Differentiation V(D)J Recombination Cell Competition In A Multicellular Organism Histone H2A-T120 Phosphorylation	Transcription, DNA-templated RRNA Processing Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Histone H4-K20 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Stem Cell Differentiation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma ( 32296059)	Acne (severe) ( 24927181)
Interacting Genes		22 interacting genes: ATM ATR CCP110 EXO1 FOXM1 H3-3A H3-4 H3C1 HLTF IMPDH2 KATNA1 NF2 PRKDC PWP1 PYGO2 RAG1 RBX1 SAMHD1 TET2 TP53 UBE2D2 UBE2D3	9 interacting genes: APP CKAP4 CUL4B DAPK1 DCAF1 HOXA3 NFYA OGT SMURF1
Entrez ID		9730	11137
HPRD ID		11674	11464
Ensembl ID		ENSG00000145041	ENSG00000136045
Uniprot IDs		Q9Y4B6	A0A024RBH5 B4DJV5 Q13610
PDB IDs		3WA0 4CC9 4P7I 4PXW 4Z8L 5AJA 5JK7 6N45
Enriched GO Terms of Interacting Partners?
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