TRIP11 and ASB2

		TRIP11	ASB2
Description		thyroid hormone receptor interactor 11	ankyrin repeat and SOCS box containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Inner Acrosomal Membrane Outer Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Cytoskeleton Nuclear Speck Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Ubiquitin Ligase Complex Cytosol
	Molecular Function	Transcription Coactivator Activity Protein Binding Small GTPase Binding	Protein Binding Ubiquitin Protein Ligase Activity Cullin Family Protein Binding
	Biological Process	Ventricular Septum Development Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Transcription By RNA Polymerase II Protein Glycosylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Positive Regulation Of Transcription, DNA-templated Cartilage Development Inner Ear Receptor Cell Stereocilium Organization Golgi Ribbon Formation Vesicle Tethering To Golgi	Heart Looping Ubiquitin-dependent Protein Catabolic Process Signal Transduction Protein Ubiquitination Actin Cytoskeleton Reorganization Intracellular Signal Transduction Skeletal Muscle Cell Differentiation Dendritic Cell Migration Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cardiac Muscle Cell Differentiation Cardiac Muscle Cell Development Podosome Assembly
Pathways		Intraflagellar transport Intra-Golgi traffic Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) FEV1 ( 30804560) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 28552196 20881960 25282103 25429064 31562340 18391950 18391951) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082 30804560) Major depressive disorder ( 34099189) Major depressive disorder x sex interaction ( 34099189) Refractive error ( 32231278) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)	Aspartate aminotransferase levels ( 33547301) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		10 interacting genes: ARNT ASB2 ATXN1L EPS8 GPR65 MYBPC2 PSMC5 RB1 SERPINA4 THRA	7 interacting genes: ELOB FLNA FLNB SMAD9 TRIP11 UBC UBE2D1
Entrez ID		9321	51676
HPRD ID		05143	05768
Ensembl ID		ENSG00000100815	ENSG00000100628
Uniprot IDs		Q15643	A0A024R6E7 Q96Q27
PDB IDs
Enriched GO Terms of Interacting Partners?
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