ASB2 and TRIP11

		ASB2	TRIP11
Description		ankyrin repeat and SOCS box containing 2	thyroid hormone receptor interactor 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytosol	Golgi Membrane Inner Acrosomal Membrane Outer Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Cytoskeleton Nuclear Speck Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity Cullin Family Protein Binding	Transcription Coactivator Activity Protein Binding Small GTPase Binding
	Biological Process	Heart Looping Ubiquitin-dependent Protein Catabolic Process Signal Transduction Protein Ubiquitination Actin Cytoskeleton Reorganization Intracellular Signal Transduction Skeletal Muscle Cell Differentiation Dendritic Cell Migration Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cardiac Muscle Cell Differentiation Cardiac Muscle Cell Development Podosome Assembly	Ventricular Septum Development Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Transcription By RNA Polymerase II Protein Glycosylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Positive Regulation Of Transcription, DNA-templated Cartilage Development Inner Ear Receptor Cell Stereocilium Organization Golgi Ribbon Formation Vesicle Tethering To Golgi
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Intraflagellar transport Intra-Golgi traffic Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Sum eosinophil basophil counts ( 27863252)	Body size at age 10 ( 32376654) FEV1 ( 30804560) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 28552196 20881960 25282103 25429064 31562340 18391950 18391951) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082 30804560) Major depressive disorder ( 34099189) Major depressive disorder x sex interaction ( 34099189) Refractive error ( 32231278) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
Interacting Genes		7 interacting genes: ELOB FLNA FLNB SMAD9 TRIP11 UBC UBE2D1	10 interacting genes: ARNT ASB2 ATXN1L EPS8 GPR65 MYBPC2 PSMC5 RB1 SERPINA4 THRA
Entrez ID		51676	9321
HPRD ID		05768	05143
Ensembl ID		ENSG00000100628	ENSG00000100815
Uniprot IDs		A0A024R6E7 Q96Q27	Q15643
PDB IDs
Enriched GO Terms of Interacting Partners?
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