TRIP11 and GPR65

		TRIP11	GPR65
Description		thyroid hormone receptor interactor 11	G protein-coupled receptor 65
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Inner Acrosomal Membrane Outer Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Cytoskeleton Nuclear Speck Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding Small GTPase Binding	G Protein-coupled Receptor Activity
	Biological Process	Ventricular Septum Development Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Transcription By RNA Polymerase II Protein Glycosylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Positive Regulation Of Transcription, DNA-templated Cartilage Development Inner Ear Receptor Cell Stereocilium Organization Golgi Ribbon Formation Vesicle Tethering To Golgi	Apoptotic Process Immune Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Response To Acidic PH Actin Cytoskeleton Reorganization Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Stress Fiber Assembly Activation Of GTPase Activity
Pathways		Intraflagellar transport Intra-Golgi traffic Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) FEV1 ( 30804560) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 28552196 20881960 25282103 25429064 31562340 18391950 18391951) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082 30804560) Major depressive disorder ( 34099189) Major depressive disorder x sex interaction ( 34099189) Refractive error ( 32231278) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)	Ankylosing spondylitis ( 23749187) California verbal learning test score ( 31596458) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Crohn's disease ( 28067908 21102463) Degraded stimulus continuous performance test score ( 31596458) Diastolic blood pressure night-to-day ratio in hypertension ( 29973135) Eosinophil percentage of white cells ( 32888494) Food antigen IgG levels ( 24962563) Inflammatory bowel disease ( 28067908 23128233) Multiple sclerosis ( 21833088) Parkinson's disease ( 32201043) Takayasu arteritis ( 25604533)
Interacting Genes		10 interacting genes: ARNT ASB2 ATXN1L EPS8 GPR65 MYBPC2 PSMC5 RB1 SERPINA4 THRA	2 interacting genes: CKB TRIP11
Entrez ID		9321	8477
HPRD ID		05143	07057
Ensembl ID		ENSG00000100815	ENSG00000140030
Uniprot IDs		Q15643	B5B0C2 Q8IYL9
PDB IDs
Enriched GO Terms of Interacting Partners?
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