ZW10 and ZWINT

Number of citations of the paper that reports this interaction (PubMedID 15824131)
116

Data Source:
HPRD (in vivo, in vitro)

		ZW10	ZWINT
Description		zw10 kinetochore protein	ZW10 interacting kinetochore protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Kinetochore Microtubule Cytosol Membrane Dsl1/NZR Complex RZZ Complex	Kinetochore Nucleoplasm Cytoplasm Cytosol Nuclear Body Dendrite
	Molecular Function	Protein Binding Centromeric DNA Binding	Protein Binding Protein N-terminus Binding
	Biological Process	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Mitotic Metaphase Plate Congression Mitotic Cell Cycle Checkpoint Signaling Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Exit From Mitosis Protein Transport Protein Localization To Kinetochore Cell Division Meiotic Cell Cycle Protein-containing Complex Assembly	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Checkpoint Signaling Mitotic Spindle Assembly Checkpoint Signaling Cell Division Establishment Of Localization In Cell
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) ( 32678081) Parental longevity (father's attained age) ( 29227965)	Cardiac hypertrophy ( 21348951) Cognitive function in longevity ( 33607172) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Liver fibrosis (total hepatic collagen content) ( 32953199)
Interacting Genes		7 interacting genes: APP DCTN2 PIAS4 PTF1A RINT1 ZWILCH ZWINT	17 interacting genes: APP BCAS2 BFSP1 CCHCR1 CLU DSN1 FAM90A1 KRT75 LIG4 MAFB MIS12 MSGN1 NDC80 NUP54 PHAX TSG101 ZW10
Entrez ID		9183	11130
HPRD ID		04902	18366
Ensembl ID		ENSG00000086827	ENSG00000122952
Uniprot IDs		O43264	O95229
PDB IDs
Enriched GO Terms of Interacting Partners?
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