ZW10 and PTF1A

Number of citations of the paper that reports this interaction (PubMedID 25355311)
8

Data Source:
BioGRID (two hybrid)

		ZW10	PTF1A
Description		zw10 kinetochore protein	pancreas associated transcription factor 1a
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Kinetochore Microtubule Cytosol Membrane Dsl1/NZR Complex RZZ Complex	Chromatin Nucleus Transcription Regulator Complex Cytoplasm
	Molecular Function	Protein Binding Centromeric DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Mitotic Metaphase Plate Congression Mitotic Cell Cycle Checkpoint Signaling Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Exit From Mitosis Protein Transport Protein Localization To Kinetochore Cell Division Meiotic Cell Cycle Protein-containing Complex Assembly	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Tissue Development Retina Layer Formation Cerebellum Development Pancreas Development Exocrine Pancreas Development Developmental Process Amacrine Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Neuron Fate Commitment Regulation Of Neural Retina Development
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Regulation of gene expression in early pancreatic precursor cells
Drugs
Diseases
GWAS		Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) ( 32678081) Parental longevity (father's attained age) ( 29227965)	Type 2 diabetes ( 32499647)
Interacting Genes		7 interacting genes: APP DCTN2 PIAS4 PTF1A RINT1 ZWILCH ZWINT	12 interacting genes: AAMP CCDC27 CCNDBP1 KAT2B PALS2 RBPJ RPGRIP1 SPATA7 TCF12 TCF4 TRIP12 ZW10
Entrez ID		9183	256297
HPRD ID		04902	09526
Ensembl ID		ENSG00000086827	ENSG00000168267
Uniprot IDs		O43264	Q7RTS3
PDB IDs
Enriched GO Terms of Interacting Partners?
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