ZWINT and MSGN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZWINT	MSGN1
Description		ZW10 interacting kinetochore protein	mesogenin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleoplasm Cytoplasm Cytosol Nuclear Body Dendrite	Chromatin Nucleus
	Molecular Function	Protein Binding Protein N-terminus Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Checkpoint Signaling Mitotic Spindle Assembly Checkpoint Signaling Cell Division Establishment Of Localization In Cell	Mesoderm Formation Somitogenesis Regulation Of Transcription By RNA Polymerase II Segment Specification Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Cognitive function in longevity ( 33607172) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Liver fibrosis (total hepatic collagen content) ( 32953199)	Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699)
Interacting Genes		17 interacting genes: APP BCAS2 BFSP1 CCHCR1 CLU DSN1 FAM90A1 KRT75 LIG4 MAFB MIS12 MSGN1 NDC80 NUP54 PHAX TSG101 ZW10	30 interacting genes: AP1B1 ATP11B BRAT1 CCDC172 CTAG1A CTAG1B DNALI1 EXOC7 FERD3L HAP1 ID1 ID2 ID3 IGFBP6 ITGB3BP LDOC1 MAGEA6 MYF5 MYL9 NECAB2 OST4 SERTAD3 TCF12 TCF4 TEPSIN TEX12 TRAF1 TTC23L ZMYND12 ZWINT
Entrez ID		11130	343930
HPRD ID		18366
Ensembl ID		ENSG00000122952	ENSG00000151379
Uniprot IDs		O95229	A6NI15
PDB IDs
Enriched GO Terms of Interacting Partners?
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